MitoProteome Database

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MT000001

Gene Information

Entrez Gene ID18
Gene Name4-aminobutyrate aminotransferase
Gene SymbolABAT
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0032144 IDA:UniProtKBC4-aminobutyrate transaminase complex
GO:0070062 IDA:UniProtCextracellular vesicular exosome
GO:0005759 TAS:ReactomeCmitochondrial matrix
GO:0005739 ISS:UniProtKBCmitochondrion
GO:0043005 IEA:EnsemblCneuron projection
GO:0003867 TAS:ReactomeF4-aminobutyrate transaminase activity
GO:0042803 IPI:UniProtKBFprotein homodimerization activity
GO:0030170 IDA:UniProtKBFpyridoxal phosphate binding
GO:0047298 IEA:UniProtKB-ECF(S)-3-amino-2-methylpropionate transaminase activity
GO:0032145 ISS:UniProtKBFsuccinate-semialdehyde dehydrogenase binding
GO:0048148 ISS:UniProtKBPbehavioral response to cocaine
GO:0007620 IEA:EnsemblPcopulation
GO:0009450 NAS:UniProtKBPgamma-aminobutyric acid catabolic process
GO:0007626 IEA:EnsemblPlocomotory behavior
GO:0045776 IEA:EnsemblPnegative regulation of blood pressure
GO:0042135 NAS:UniProtKBPneurotransmitter catabolic process
GO:0007269 TAS:ReactomePneurotransmitter secretion
GO:0042493 IEA:EnsemblPresponse to drug
GO:0045471 IEA:EnsemblPresponse to ethanol
GO:0001666 IEA:EnsemblPresponse to hypoxia
GO:0010039 IEA:EnsemblPresponse to iron ion
GO:0035094 IEA:EnsemblPresponse to nicotine
GO:0007268 TAS:ReactomePsynaptic transmission
KEGG Pathway Links
KEGG Pathway IDDescription
hsa00250Alanine, aspartate and glutamate metabolism
ko00250Alanine, aspartate and glutamate metabolism
hsa00410beta-Alanine metabolism
ko00410beta-Alanine metabolism
hsa00650Butanoate metabolism
ko00650Butanoate metabolism
hsa04727GABAergic synapse
ko04727GABAergic synapse
hsa_M00027GABA (gamma-Aminobutyrate) shunt
M00027GABA (gamma-Aminobutyrate) shunt
hsa01100Metabolic pathways
hsa00640Propanoate metabolism
ko00640Propanoate metabolism
hsa00280Valine, leucine and isoleucine degradation
ko00280Valine, leucine and isoleucine degradation
BIOCYC Pathway Links
BIOCYC Pathway IDDescription
PWY-65354-aminobutyrate degradation
PWY-65354-aminobutyrate degradation I
BETA-ALA-DEGRADATION-I-PWYbeta-alanine degradation I
GLUDEG-I-PWYGABA shunt
GLUDEG-I-PWYglutamate degradation III (via 4-aminobutyrate)
VALDEG-PWYvaline degradation I
VALDEG-PWYvaline degradation I
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_23964Degradation of GABA
REACT_23947GABA synthesis, release, reuptake and degradation
REACT_13685Neuronal System
REACT_13723Neurotransmitter Release Cycle
REACT_13477Transmission across Chemical Synapses