MitoProteome Database

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MT000003

Gene Information

Entrez Gene ID25
Gene NameABL proto-oncogene 1, non-receptor tyrosine kinase
Gene SymbolABL1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0015629 TAS:UniProtKBCactin cytoskeleton
GO:0031252 IEA:EnsemblCcell leading edge
GO:0005737 TAS:UniProtKBCcytoplasm
GO:0005829 IDA:MGICcytosol
GO:0016020 IEA:UniProtKB-KWCmembrane
GO:0005739 NAS:ParkinsonsUK-UCLCmitochondrion
GO:0005730 IDA:MGICnucleolus
GO:0005634 IDA:UniProtKBCnucleus
GO:0048471 IDA:UniProtKBCperinuclear region of cytoplasm
GO:0003785 TAS:UniProtKBFactin monomer binding
GO:0005524 IDA:UniProtKBFATP binding
GO:0003677 NAS:UniProtKBFDNA binding
GO:0000287 IDA:UniProtKBFmagnesium ion binding
GO:0030145 IDA:UniProtKBFmanganese ion binding
GO:0051019 IPI:BHF-UCLFmitogen-activated protein kinase binding
GO:0004515 TAS:UniProtKBFnicotinate-nucleotide adenylyltransferase activity
GO:0004715 IDA:UniProtKBFnon-membrane spanning protein tyrosine kinase activity
GO:0070064 IDA:UniProtKBFproline-rich region binding
GO:0008022 IPI:UniProtKBFprotein C-terminus binding
GO:0004672 IDA:MGIFprotein kinase activity
GO:0004713 IDA:UniProtKBFprotein tyrosine kinase activity
GO:0017124 IPI:UniProtKBFSH3 domain binding
GO:0019905 IPI:UniProtKBFsyntaxin binding
GO:0030036 ISS:UniProtKBPactin cytoskeleton organization
GO:0006914 IEA:UniProtKB-KWPautophagy
GO:0007411 TAS:ReactomePaxon guidance
GO:0007596 TAS:ReactomePblood coagulation
GO:0007155 IEA:UniProtKB-KWPcell adhesion
GO:0007050 TAS:ParkinsonsUK-UCLPcell cycle arrest
GO:0006464 NAS:UniProtKBPcellular protein modification process
GO:0006974 IDA:UniProtKBPcellular response to DNA damage stimulus
GO:1903351 TAS:ParkinsonsUK-UCLPcellular response to dopamine
GO:0034599 TAS:ParkinsonsUK-UCLPcellular response to oxidative stress
GO:0006975 IDA:UniProtKBPDNA damage induced protein phosphorylation
GO:0038096 TAS:ReactomePFc-gamma receptor signaling pathway involved in phagocytosis
GO:0045087 TAS:ReactomePinnate immune response
GO:0008630 TAS:UniProtKBPintrinsic apoptotic signaling pathway in response to DNA damage
GO:0006298 TAS:ProtIncPmismatch repair
GO:0051882 TAS:ParkinsonsUK-UCLPmitochondrial depolarization
GO:0007067 TAS:ParkinsonsUK-UCLPmitotic nuclear division
GO:0042692 TAS:ReactomePmuscle cell differentiation
GO:1900275 IMP:MGIPnegative regulation of phospholipase C activity
GO:0071901 IDA:BHF-UCLPnegative regulation of protein serine/threonine kinase activity
GO:0051444 TAS:ParkinsonsUK-UCLPnegative regulation of ubiquitin-protein transferase activity
GO:0018108 IDA:UniProtKBPpeptidyl-tyrosine phosphorylation
GO:0048008 IEA:EnsemblPplatelet-derived growth factor receptor signaling pathway
GO:0043065 IDA:UniProtKBPpositive regulation of apoptotic process
GO:0007204 IMP:MGIPpositive regulation of cytosolic calcium ion concentration
GO:0051149 TAS:ReactomePpositive regulation of muscle cell differentiation
GO:0051353 IDA:BHF-UCLPpositive regulation of oxidoreductase activity
GO:0050731 IDA:UniProtKBPpositive regulation of peptidyl-tyrosine phosphorylation
GO:2000249 TAS:UniProtKBPregulation of actin cytoskeleton reorganization
GO:0010506 TAS:UniProtKBPregulation of autophagy
GO:0030155 TAS:UniProtKBPregulation of cell adhesion
GO:2000145 TAS:UniProtKBPregulation of cell motility
GO:0030100 TAS:UniProtKBPregulation of endocytosis
GO:2001020 IDA:UniProtKBPregulation of response to DNA damage stimulus
GO:0006355 TAS:ProtIncPregulation of transcription, DNA-templated
GO:0006979 IGI:MGIPresponse to oxidative stress
GO:0042770 IDA:UniProtKBPsignal transduction in response to DNA damage
KEGG Pathway Links
KEGG Pathway IDDescription
hsa04360Axon guidance
ko04360Axon guidance
hsa04110Cell cycle
ko04110Cell cycle
hsa05220Chronic myeloid leukemia
ko05220Chronic myeloid leukemia
hsa04012ErbB signaling pathway
ko04012ErbB signaling pathway
hsa05206MicroRNAs in cancer
ko05206MicroRNAs in cancer
hsa04722Neurotrophin signaling pathway
ko04722Neurotrophin signaling pathway
hsa05130Pathogenic Escherichia coli infection
ko05130Pathogenic Escherichia coli infection
hsa05200Pathways in cancer
hsa04014Ras signaling pathway
hsa05131Shigellosis
hsa05416Viral myocarditis
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18266Axon guidance
REACT_21402CDO in myogenesis
REACT_111045Developmental Biology
REACT_24970Factors involved in megakaryocyte development and platelet production
REACT_160123Fcgamma receptor (FCGR) dependent phagocytosis
REACT_604Hemostasis
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_21303Myogenesis
REACT_160086Regulation of actin dynamics for phagocytic cup formation
REACT_19230Role of Abl in Robo-Slit signaling
REACT_19351Signaling by Robo receptor