MitoProteome Database

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MT000005

Gene Information

Entrez Gene ID32
Gene Nameacetyl-CoA carboxylase beta
Gene SymbolACACB
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0005741 TAS:ReactomeCmitochondrial outer membrane
GO:0005739 IDA:UniProtKBCmitochondrion
GO:0005634 IDA:UniProtKBCnucleus
GO:0003989 IDA:UniProtKBFacetyl-CoA carboxylase activity
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0009374 IEA:EnsemblFbiotin binding
GO:0004075 IEA:UniProtKB-ECFbiotin carboxylase activity
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0006084 IDA:UniProtKBPacetyl-CoA metabolic process
GO:0006768 TAS:ReactomePbiotin metabolic process
GO:0006853 TAS:ReactomePcarnitine shuttle
GO:0044255 TAS:ReactomePcellular lipid metabolic process
GO:0006112 TAS:ReactomePenergy reserve metabolic process
GO:0006633 IEA:UniProtKB-KWPfatty acid biosynthetic process
GO:2001295 IEA:UniProtKB-UniPathwayPmalonyl-CoA biosynthetic process
GO:0031325 TAS:ReactomePpositive regulation of cellular metabolic process
GO:0051289 IDA:UniProtKBPprotein homotetramerization
GO:0042493 IEA:EnsemblPresponse to drug
GO:0014070 IEA:EnsemblPresponse to organic cyclic compound
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006766 TAS:ReactomePvitamin metabolic process
GO:0006767 TAS:ReactomePwater-soluble vitamin metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa04920Adipocytokine signaling pathway
ko04920Adipocytokine signaling pathway
hsa04152AMPK signaling pathway
ko04152AMPK signaling pathway
hsa00061Fatty acid biosynthesis
ko00061Fatty acid biosynthesis
hsa_M00082Fatty acid biosynthesis, initiation
M00082Fatty acid biosynthesis, initiation
hsa01212Fatty acid metabolism
ko01212Fatty acid metabolism
hsa04910Insulin signaling pathway
ko04910Insulin signaling pathway
hsa01100Metabolic pathways
hsa00640Propanoate metabolism
ko00640Propanoate metabolism
hsa00620Pyruvate metabolism
ko00620Pyruvate metabolism
BIOCYC Pathway Links
BIOCYC Pathway IDDescription
PWY0-1264biotin-carboxyl carrier protein assembly
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_147904Activation of gene expression by SREBF (SREBP)
REACT_11153Biotin transport and metabolism
REACT_2122ChREBP activates metabolic gene expression
REACT_169280Defective AMN causes hereditary megaloblastic anemia 1
REACT_169403Defective BTD causes biotidinase deficiency
REACT_169178Defective CD320 causes methylmalonic aciduria
REACT_169132Defective CUBN causes hereditary megaloblastic anemia 1
REACT_169415Defective GIF causes intrinsic factor deficiency
REACT_169312Defective HLCS causes multiple carboxylase deficiency
REACT_169363Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
REACT_169316Defective MMAA causes methylmalonic aciduria type cblA
REACT_169318Defective MMAB causes methylmalonic aciduria type cblB
REACT_169169Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
REACT_169256Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
REACT_169149Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
REACT_169439Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
REACT_169313Defective MUT causes methylmalonic aciduria mut type
REACT_169120Defective TCN2 causes hereditary megaloblastic anemia
REACT_169238Defects in biotin (Btn) metabolism
REACT_169429Defects in cobalamin (B12) metabolism
REACT_169385Defects in vitamin and cofactor metabolism
REACT_116125Disease
REACT_22279Fatty acid, triacylglycerol, and ketone body metabolism
REACT_11082Import of palmitoyl-CoA into the mitochondrial matrix
REACT_1505Integration of energy metabolism
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_11193Metabolism of vitamins and cofactors
REACT_11238Metabolism of water-soluble vitamins and cofactors
REACT_147797Regulation of cholesterol biosynthesis by SREBP (SREBF)