MitoProteome Database

MT000012

Gene Information

Entrez Gene ID47
Gene NameATP citrate lyase
Gene SymbolACLY
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009346 TAS:ProtIncCcitrate lyase complex
GO:0005737 IDA:HPACcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0016020 IDA:UniProtKBCmembrane
GO:0005739 IEA:EnsemblCmitochondrion
GO:0005634 IDA:HPACnucleus
GO:0005886 IDA:HPACplasma membrane
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0003878 TAS:UniProtKBFATP citrate synthase activity
GO:0048037 IEA:InterProFcofactor binding
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0004775 IEA:InterProFsuccinate-CoA ligase (ADP-forming) activity
GO:0006200 TAS:ProtIncPATP catabolic process
GO:0044262 IEA:InterProPcellular carbohydrate metabolic process
GO:0044255 TAS:ReactomePcellular lipid metabolic process
GO:0006101 TAS:ProtIncPcitrate metabolic process
GO:0015936 TAS:ProtIncPcoenzyme A metabolic process
GO:0006112 TAS:ReactomePenergy reserve metabolic process
GO:0008610 IDA:UniProtKBPlipid biosynthetic process
GO:0035338 TAS:ReactomePlong-chain fatty-acyl-CoA biosynthetic process
GO:0031325 TAS:ReactomePpositive regulation of cellular metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0019432 TAS:ReactomePtriglyceride biosynthetic process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa00020Citrate cycle (TCA cycle)
ko00020Citrate cycle (TCA cycle)
hsa01100Metabolic pathways
BIOCYC Pathway Links
BIOCYC Pathway IDDescription
PWY-5172acetyl-CoA biosynthesis III (from citrate)
PWY-5172acetyl-CoA biosynthesis III (from citrate)
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_2122ChREBP activates metabolic gene expression
REACT_22279Fatty acid, triacylglycerol, and ketone body metabolism
REACT_1319Fatty Acyl-CoA Biosynthesis
REACT_1505Integration of energy metabolism
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_1190Triglyceride Biosynthesis