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MitoProteome Human Mitochondrial Protein Database
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Related Proteins
MT000012
Gene Information
Entrez Gene ID
47
Gene Name
ATP citrate lyase
Gene Symbol
ACLY
Species
Homo sapiens
Gene Ontology (GO Annotations)
GO ID
Source
Type
Description
GO:0009346
TAS:ProtInc
C
citrate lyase complex
GO:0005737
IDA:HPA
C
cytoplasm
GO:0005829
TAS:Reactome
C
cytosol
GO:0070062
IDA:UniProtKB
C
extracellular vesicular exosome
GO:0016020
IDA:UniProtKB
C
membrane
GO:0005739
IEA:Ensembl
C
mitochondrion
GO:0005634
IDA:HPA
C
nucleus
GO:0005886
IDA:HPA
C
plasma membrane
GO:0005524
IEA:UniProtKB-KW
F
ATP binding
GO:0003878
TAS:UniProtKB
F
ATP citrate synthase activity
GO:0048037
IEA:InterPro
F
cofactor binding
GO:0046872
IEA:UniProtKB-KW
F
metal ion binding
GO:0004775
IEA:InterPro
F
succinate-CoA ligase (ADP-forming) activity
GO:0006200
TAS:ProtInc
P
ATP catabolic process
GO:0044262
IEA:InterPro
P
cellular carbohydrate metabolic process
GO:0044255
TAS:Reactome
P
cellular lipid metabolic process
GO:0006101
TAS:ProtInc
P
citrate metabolic process
GO:0015936
TAS:ProtInc
P
coenzyme A metabolic process
GO:0006112
TAS:Reactome
P
energy reserve metabolic process
GO:0008610
IDA:UniProtKB
P
lipid biosynthetic process
GO:0035338
TAS:Reactome
P
long-chain fatty-acyl-CoA biosynthetic process
GO:0031325
TAS:Reactome
P
positive regulation of cellular metabolic process
GO:0044281
TAS:Reactome
P
small molecule metabolic process
GO:0019432
TAS:Reactome
P
triglyceride biosynthetic process
KEGG Pathway Links
KEGG Pathway ID
Description
hsa00020
Citrate cycle (TCA cycle)
ko00020
Citrate cycle (TCA cycle)
hsa01100
Metabolic pathways
BIOCYC Pathway Links
BIOCYC Pathway ID
Description
PWY-5172
acetyl-CoA biosynthesis III (from citrate)
PWY-5172
acetyl-CoA biosynthesis III (from citrate)
REACTOME Pathway Links
REACTOME Pathway ID
Description
REACT_2122
ChREBP activates metabolic gene expression
REACT_22279
Fatty acid, triacylglycerol, and ketone body metabolism
REACT_1319
Fatty Acyl-CoA Biosynthesis
REACT_1505
Integration of energy metabolism
REACT_111217
Metabolism
REACT_22258
Metabolism of lipids and lipoproteins
REACT_1190
Triglyceride Biosynthesis
MitoProteome Human Mitochondrial Protein Database
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