MitoProteome Database

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MT000023

Gene Information

Entrez Gene ID212
Gene Name5'-aminolevulinate synthase 2
Gene SymbolALAS2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005743 IDA:UniProtKBCmitochondrial inner membrane
GO:0005759 TAS:ReactomeCmitochondrial matrix
GO:0005739 IDA:UniProtKBCmitochondrion
GO:0003870 IDA:UniProtKBF5-aminolevulinate synthase activity
GO:0050662 ISS:UniProtKBFcoenzyme binding
GO:0016594 ISS:UniProtKBFglycine binding
GO:0030170 IEA:InterProFpyridoxal phosphate binding
GO:0006879 ISS:UniProtKBPcellular iron ion homeostasis
GO:0030218 ISS:UniProtKBPerythrocyte differentiation
GO:0006783 ISS:UniProtKBPheme biosynthetic process
GO:0042541 ISS:UniProtKBPhemoglobin biosynthetic process
GO:0032364 NAS:UniProtKBPoxygen homeostasis
GO:0006778 TAS:ReactomePporphyrin-containing compound metabolic process
GO:0006782 IEA:UniProtKB-UniPathwayPprotoporphyrinogen IX biosynthetic process
GO:0001666 IDA:UniProtKBPresponse to hypoxia
GO:0044281 TAS:ReactomePsmall molecule metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa00260Glycine, serine and threonine metabolism
ko00260Glycine, serine and threonine metabolism
hsa01100Metabolic pathways
hsa00860Porphyrin and chlorophyll metabolism
ko00860Porphyrin and chlorophyll metabolism
BIOCYC Pathway Links
BIOCYC Pathway IDDescription
PWY-5920heme biosynthesis II
PWY-5920superpathway of heme biosynthesis from glycine
PWY-5189tetrapyrrole biosynthesis II
PWY-5189tetrapyrrole biosynthesis II (from glycine)
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_9465Heme biosynthesis
REACT_111217Metabolism
REACT_9431Metabolism of porphyrins