MitoProteome Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins

MT000031

UniProt Annotations

Entry Information

Gene Name	aldolase C, fructose-bisphosphate
Protein Entry	ALDOC_HUMAN
UniProt ID	P09972
Species	Human

Comments

Comment type	Description
Biophysicochemical Properties	Kinetic parameters: KM=10.7 uM for fructose 1,6-bisphosphate {ECO:0000269\|PubMed:15537755}; KM=16 mM for fructose 1-phosphate {ECO:0000269\|PubMed:15537755};
Catalytic Activity	D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate. {ECO:0000269\|PubMed:15537755}.
Miscellaneous	In vertebrates, three forms of this ubiquitous glycolytic enzyme are found, aldolase A in muscle, aldolase B in liver and aldolase C in brain.
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3- phosphate and glycerone phosphate from D-glucose: step 4/4.
Sequence Caution	Sequence=AAI03761.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Similarity	Belongs to the class I fructose-bisphosphate aldolase family. {ECO:0000305}.
Subunit	Homotetramer. Interacts with ATP6V1E1. May interact with PLD2. {ECO:0000269\|PubMed:11399750, ECO:0000269\|PubMed:11876650}.