MitoProteome Database

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MT000044

Gene Information

Entrez Gene ID411
Gene Namearylsulfatase B
Gene SymbolARSB
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005788 TAS:ReactomeCendoplasmic reticulum lumen
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005794 IEA:EnsemblCGolgi apparatus
GO:0043202 TAS:ReactomeClysosomal lumen
GO:0005764 TAS:ProtIncClysosome
GO:0005739 IEA:EnsemblCmitochondrion
GO:0005791 IEA:EnsemblCrough endoplasmic reticulum
GO:0004065 TAS:ProtIncFarylsulfatase activity
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0003943 TAS:ReactomeFN-acetylgalactosamine-4-sulfatase activity
GO:0006914 IEA:EnsemblPautophagy
GO:0005975 TAS:ReactomePcarbohydrate metabolic process
GO:0044267 TAS:ReactomePcellular protein metabolic process
GO:0007417 IEA:EnsemblPcentral nervous system development
GO:0030207 TAS:ReactomePchondroitin sulfate catabolic process
GO:0030204 TAS:ReactomePchondroitin sulfate metabolic process
GO:0030203 TAS:ReactomePglycosaminoglycan metabolic process
GO:0006687 TAS:ReactomePglycosphingolipid metabolic process
GO:0007041 TAS:ProtIncPlysosomal transport
GO:0007040 TAS:ProtIncPlysosome organization
GO:0043687 TAS:ReactomePpost-translational protein modification
GO:0043627 IEA:EnsemblPresponse to estrogen
GO:0051597 IEA:EnsemblPresponse to methylmercury
GO:0007584 IEA:EnsemblPresponse to nutrient
GO:0009268 IEA:EnsemblPresponse to pH
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006665 TAS:ReactomePsphingolipid metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa_M00077Chondroitin sulfate degradation
M00077Chondroitin sulfate degradation
hsa_M00076Dermatan sulfate degradation
M00076Dermatan sulfate degradation
hsa00531Glycosaminoglycan degradation
ko00531Glycosaminoglycan degradation
hsa04142Lysosome
ko04142Lysosome
hsa01100Metabolic pathways
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_121206Chondroitin sulfate/dermatan sulfate metabolism
REACT_120888CS/DS degradation
REACT_116125Disease
REACT_200833Glycogen storage diseases
REACT_121315Glycosaminoglycan metabolism
REACT_116105Glycosphingolipid metabolism
REACT_111217Metabolism
REACT_474Metabolism of carbohydrates
REACT_22258Metabolism of lipids and lipoproteins
REACT_17015Metabolism of proteins
REACT_147857MPS I - Hurler syndrome
REACT_147734MPS II - Hunter syndrome
REACT_147753MPS IIIA - Sanfilippo syndrome A
REACT_147788MPS IIIB - Sanfilippo syndrome B
REACT_147860MPS IIIC - Sanfilippo syndrome C
REACT_147749MPS IIID - Sanfilippo syndrome D
REACT_147825MPS IV - Morquio syndrome A
REACT_147798MPS IV - Morquio syndrome B
REACT_147739MPS IX - Natowicz syndrome
REACT_147759MPS VII - Sly syndrome
REACT_147719MPS VI - Maroteaux-Lamy syndrome
REACT_147853Mucopolysaccharidoses
REACT_200783Myoclonic epilepsy of Lafora
REACT_22161Post-translational protein modification
REACT_1069PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
REACT_19323Sphingolipid metabolism
REACT_121036The activation of arylsulfatases