MitoProteome Database

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MT000047

Gene Information

Entrez Gene ID471
Gene Name5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Gene SymbolATIC
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0016020 IDA:UniProtKBCmembrane
GO:0005739 IEA:EnsemblCmitochondrion
GO:0003937 TAS:ReactomeFIMP cyclohydrolase activity
GO:0004643 TAS:ReactomeFphosphoribosylaminoimidazolecarboxamide formyltransferase activity
GO:0042803 IPI:UniProtKBFprotein homodimerization activity
GO:0003360 IEA:EnsemblPbrainstem development
GO:0021549 IEA:EnsemblPcerebellum development
GO:0021987 IEA:EnsemblPcerebral cortex development
GO:0006189 IEA:UniProtKB-UniPathwayP'de novo' IMP biosynthetic process
GO:0046452 IEA:EnsemblPdihydrofolate metabolic process
GO:0006139 TAS:ProtIncPnucleobase-containing compound metabolic process
GO:0055086 TAS:ReactomePnucleobase-containing small molecule metabolic process
GO:0009116 IEA:EnsemblPnucleoside metabolic process
GO:0031100 IEA:EnsemblPorgan regeneration
GO:0006144 TAS:ReactomePpurine nucleobase metabolic process
GO:0009168 TAS:ReactomePpurine ribonucleoside monophosphate biosynthetic process
GO:0010035 IEA:EnsemblPresponse to inorganic substance
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0046654 IEA:EnsemblPtetrahydrofolate biosynthetic process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa_M00048Inosine monophosphate biosynthesis, PRPP + glutamine => IMP
M00048Inosine monophosphate biosynthesis, PRPP + glutamine => IMP
hsa01100Metabolic pathways
hsa00670One carbon pool by folate
ko00670One carbon pool by folate
hsa00230Purine metabolism
ko00230Purine metabolism
BIOCYC Pathway Links
BIOCYC Pathway IDDescription
PWY-6124inosine-5'-phosphate biosynthesis II
PWY-6124inosine-5'-phosphate biosynthesis II
PWY-841purine nucleotides de novo biosynthesis II
PWY-841superpathway of purine nucleotides de novo biosynthesis I
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111217Metabolism
REACT_1698Metabolism of nucleotides
REACT_522Purine metabolism
REACT_1776Purine ribonucleoside monophosphate biosynthesis