MitoProteome Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MT000048

Gene Information

Entrez Gene ID487
Gene NameATPase, Ca++ transporting, cardiac muscle, fast twitch 1
Gene SymbolATP2A1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0034704 IC:BHF-UCLCcalcium channel complex
GO:0005793 ISS:UniProtKBCendoplasmic reticulum-Golgi intermediate compartment
GO:0005789 IDA:UniProtKBCendoplasmic reticulum membrane
GO:0031673 IDA:UniProtKBCH zone
GO:0031674 IDA:UniProtKBCI band
GO:0016021 NAS:UniProtKBCintegral component of membrane
GO:0016020 ISS:UniProtKBCmembrane
GO:0048471 ISS:UniProtKBCperinuclear region of cytoplasm
GO:0031095 TAS:ReactomeCplatelet dense tubular network membrane
GO:0016529 ISS:UniProtKBCsarcoplasmic reticulum
GO:0033017 TAS:BHF-UCLCsarcoplasmic reticulum membrane
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0005509 IMP:UniProtKBFcalcium ion binding
GO:0005388 IDA:UniProtKBFcalcium-transporting ATPase activity
GO:0042803 IPI:BHF-UCLFprotein homodimerization activity
GO:0008637 IMP:BHF-UCLPapoptotic mitochondrial changes
GO:0006200 ISS:UniProtKBPATP catabolic process
GO:0007596 TAS:ReactomePblood coagulation
GO:0070509 IMP:BHF-UCLPcalcium ion import
GO:0070588 IDA:GOCPcalcium ion transmembrane transport
GO:0006816 IDA:UniProtKBPcalcium ion transport
GO:0070059 IMP:BHF-UCLPintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0034220 TAS:ReactomePion transmembrane transport
GO:0051659 IMP:BHF-UCLPmaintenance of mitochondrion location
GO:0032471 IMP:BHF-UCLPnegative regulation of endoplasmic reticulum calcium ion concentration
GO:0045988 IMP:UniProtKBPnegative regulation of striated muscle contraction
GO:0032470 IMP:BHF-UCLPpositive regulation of endoplasmic reticulum calcium ion concentration
GO:0031448 IDA:UniProtKBPpositive regulation of fast-twitch skeletal muscle fiber contraction
GO:0051561 IMP:BHF-UCLPpositive regulation of mitochondrial calcium ion concentration
GO:0006942 IMP:UniProtKBPregulation of striated muscle contraction
GO:0090076 IDA:BHF-UCLPrelaxation of skeletal muscle
GO:0034976 IMP:BHF-UCLPresponse to endoplasmic reticulum stress
GO:0055085 TAS:ReactomePtransmembrane transport
KEGG Pathway Links
KEGG Pathway IDDescription
hsa05010Alzheimer's disease
ko05010Alzheimer's disease
hsa04020Calcium signaling pathway
ko04020Calcium signaling pathway
hsa04022cGMP-PKG signaling pathway
ko04022cGMP-PKG signaling pathway
hsa04972Pancreatic secretion
ko04972Pancreatic secretion
BIOCYC Pathway Links
BIOCYC Pathway IDDescription
PWY-6166calcium transport I
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_604Hemostasis
REACT_25300Ion channel transport
REACT_25149Ion transport by P-type ATPases
REACT_23905Platelet calcium homeostasis
REACT_23876Platelet homeostasis
REACT_118744Pre-NOTCH Expression and Processing
REACT_118798Pre-NOTCH Processing in Golgi
REACT_23765Reduction of cytosolic Ca++ levels
REACT_299Signaling by NOTCH
REACT_111102Signal Transduction
REACT_15518Transmembrane transport of small molecules