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MitoProteome Human Mitochondrial Protein Database
MitoProteome Database
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Related Proteins
MT000049
Gene Information
Entrez Gene ID
498
Gene Name
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
Gene Symbol
ATP5A1
Species
Homo sapiens
Gene Ontology (GO Annotations)
GO ID
Source
Type
Description
GO:0070062
IDA:UniProtKB
C
extracellular vesicular exosome
GO:0016020
IDA:UniProtKB
C
membrane
GO:0005743
IDA:UniProtKB
C
mitochondrial inner membrane
GO:0005759
TAS:Reactome
C
mitochondrial matrix
GO:0005753
IDA:UniProtKB
C
mitochondrial proton-transporting ATP synthase complex
GO:0005739
NAS:UniProtKB
C
mitochondrion
GO:0005886
IDA:UniProtKB
C
plasma membrane
GO:0045261
IEA:UniProtKB-KW
C
proton-transporting ATP synthase complex, catalytic core F(1)
GO:0005524
ISS:UniProtKB
F
ATP binding
GO:0042288
IDA:UniProtKB
F
MHC class I protein binding
GO:0044822
IDA:UniProtKB
F
poly(A) RNA binding
GO:0046961
IEA:InterPro
F
proton-transporting ATPase activity, rotational mechanism
GO:0046933
ISS:UniProtKB
F
proton-transporting ATP synthase activity, rotational mechanism
GO:0022857
IC:UniProtKB
F
transmembrane transporter activity
GO:0006754
NAS:UniProtKB
P
ATP biosynthetic process
GO:0006200
IDA:GOC
P
ATP catabolic process
GO:0015991
IEA:InterPro
P
ATP hydrolysis coupled proton transport
GO:0044237
TAS:Reactome
P
cellular metabolic process
GO:0009790
ISS:UniProtKB
P
embryo development
GO:0006629
ISS:UniProtKB
P
lipid metabolic process
GO:0042776
IC:UniProtKB
P
mitochondrial ATP synthesis coupled proton transport
GO:0001937
IMP:UniProtKB
P
negative regulation of endothelial cell proliferation
GO:0022904
TAS:Reactome
P
respiratory electron transport chain
GO:0044281
TAS:Reactome
P
small molecule metabolic process
KEGG Pathway Links
KEGG Pathway ID
Description
hsa05010
Alzheimer's disease
ko05010
Alzheimer's disease
hsa_M00158
F-type ATPase, eukaryotes
M00158
F-type ATPase, eukaryotes
hsa05016
Huntington's disease
ko05016
Huntington's disease
hsa01100
Metabolic pathways
hsa00190
Oxidative phosphorylation
ko00190
Oxidative phosphorylation
hsa05012
Parkinson's disease
REACTOME Pathway Links
REACTOME Pathway ID
Description
REACT_6759
Formation of ATP by chemiosmotic coupling
REACT_111217
Metabolism
REACT_17015
Metabolism of proteins
REACT_118595
Mitochondrial protein import
REACT_6305
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
REACT_111083
The citric acid (TCA) cycle and respiratory electron transport
MitoProteome Human Mitochondrial Protein Database
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