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MT000053

Record overview

MITO IDMT000053
Gene ID513
SpeciesHomo sapiens (Human)
Gene NameATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
Gene SymbolATP5D
Alternate namesATP synthase subunit delta, mitochondrial; F-ATPase delta subunit; mitochondrial ATP synthase, delta subunit; mitochondrial ATP synthase complex delta-subunit precusor;
Chromosome19
Map Location19p13.3
SummaryThis gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the delta subunit of the catalytic core. Alternatively spliced transcript variants encoding the same isoform have been identified. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for ATP5D

Proteins

ATP synthase subunit delta, mitochondrial precursor
Refseq ID:NP_001678
Protein GI:4502297
UniProt ID:P30049
mRNA ID:NM_001687
Length:168
RefSeq Status:
MLPAALLRRPGLGRLVRHARAYAEAAAAPAAASGPNQMSFTFASPTQVFFNGANVRQVDVPTLTGAFGILAAHVPTLQVLRPGLVVVHAEDGTTSKYFVS
SGSIAVNADSSVQLLAEEAVTLDMLDLGAAKANLEKAQAELVGTADEATRAEIQIRIEANEALVKALE
 
N
transit_peptide: 1..22
calculated_mol_wt: 2488
peptide sequence: 
MLPAALLRRPGLGRLVRHARAY

mat_peptide: 23..168
product: ATP synthase subunit delta, mitochondrial
calculated_mol_wt: 15020
peptide sequence: 
AEAAAAPAAASGPNQMSFTFASPTQVFFNGANVRQVDVPTLTGAFGILAAHVPTLQVLRPGLVVVHAEDGTTSKYFVSSGSIAVNADSSVQLLAEEAVTL
DMLDLGAAKANLEKAQAELVGTADEATRAEIQIRIEANEALVKALE

transit_peptide: 1..22
calculated_mol_wt: 2488
peptide sequence: 
MLPAALLRRPGLGRLVRHARAY

mat_peptide: 23..168
product: ATP synthase subunit delta, mitochondrial
calculated_mol_wt: 15020
peptide sequence: 
AEAAAAPAAASGPNQMSFTFASPTQVFFNGANVRQVDVPTLTGAFGILAAHVPTLQVLRPGLVVVHAEDGTTSKYFVSSGSIAVNADSSVQLLAEEAVTL
DMLDLGAAKANLEKAQAELVGTADEATRAEIQIRIEANEALVKALE
 
ATP synthase subunit delta, mitochondrial precursor
Refseq ID:NP_001001975
Protein GI:50345991
UniProt ID:P30049
mRNA ID:NM_001001975
Length:168
RefSeq Status:
Protein sequence is identical to GI:4502297 (mRNA isoform)
 
N
transit_peptide: 1..22
calculated_mol_wt: 2488
peptide sequence: 
MLPAALLRRPGLGRLVRHARAY

mat_peptide: 23..168
product: ATP synthase subunit delta, mitochondrial
calculated_mol_wt: 15020
peptide sequence: 
AEAAAAPAAASGPNQMSFTFASPTQVFFNGANVRQVDVPTLTGAFGILAAHVPTLQVLRPGLVVVHAEDGTTSKYFVSSGSIAVNADSSVQLLAEEAVTL
DMLDLGAAKANLEKAQAELVGTADEATRAEIQIRIEANEALVKALE