MitoProteome Database

MT000082

Gene Information

Entrez Gene ID	627
Gene Name	brain-derived neurotrophic factor
Gene Symbol	BDNF
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	ISS:UniProtKB	C	cytoplasm
GO:0005576	IEA:UniProtKB-KW	C	extracellular region
GO:0048471	ISS:UniProtKB	C	perinuclear region of cytoplasm
GO:0008021	IEA:Ensembl	C	synaptic vesicle
GO:0008083	TAS:ProtInc	F	growth factor activity
GO:0048675	IEA:Ensembl	P	axon extension
GO:0007411	IEA:Ensembl	P	axon guidance
GO:0007412	IEA:Ensembl	P	axon target recognition
GO:0001662	IEA:Ensembl	P	behavioral fear response
GO:0002544	IEA:Ensembl	P	chronic inflammatory response
GO:0007623	IEA:Ensembl	P	circadian rhythm
GO:0016358	IEA:Ensembl	P	dendrite development
GO:0097484	IEA:Ensembl	P	dendrite extension
GO:0007631	IEA:Ensembl	P	feeding behavior
GO:0007214	IEA:Ensembl	P	gamma-aminobutyric acid signaling pathway
GO:0014047	IEA:Ensembl	P	glutamate secretion
GO:0048839	IEA:Ensembl	P	inner ear development
GO:0007611	IEA:Ensembl	P	learning or memory
GO:0042490	IEA:Ensembl	P	mechanoreceptor differentiation
GO:0006120	IEA:Ensembl	P	mitochondrial electron transport, NADH to ubiquinone
GO:0007406	IEA:Ensembl	P	negative regulation of neuroblast proliferation
GO:0043524	IEA:Ensembl	P	negative regulation of neuron apoptotic process
GO:0045843	IEA:Ensembl	P	negative regulation of striated muscle tissue development
GO:0032229	IEA:Ensembl	P	negative regulation of synaptic transmission, GABAergic
GO:0021675	IEA:Ensembl	P	nerve development
GO:0007399	TAS:ProtInc	P	nervous system development
GO:0008038	IEA:Ensembl	P	neuron recognition
GO:0048170	IEA:Ensembl	P	positive regulation of long-term neuronal synaptic plasticity
GO:0045666	IEA:Ensembl	P	positive regulation of neuron differentiation
GO:0033138	IEA:Ensembl	P	positive regulation of peptidyl-serine phosphorylation
GO:0051965	IDA:BHF-UCL	P	positive regulation of synapse assembly
GO:0060079	IEA:Ensembl	P	regulation of excitatory postsynaptic membrane potential
GO:0046668	IEA:Ensembl	P	regulation of retinal cell programmed cell death
GO:0048172	IEA:Ensembl	P	regulation of short-term neuronal synaptic plasticity
GO:0072347	IEA:Ensembl	P	response to anesthetic
GO:0014076	IEA:Ensembl	P	response to fluoxetine
GO:0009725	IEA:Ensembl	P	response to hormone
GO:0055093	IEA:Ensembl	P	response to hyperoxia
GO:0001666	IEA:Ensembl	P	response to hypoxia
GO:0033189	IEA:Ensembl	P	response to vitamin A
GO:0061193	IEA:Ensembl	P	taste bud development
GO:0001657	IEA:Ensembl	P	ureteric bud development

KEGG Pathway Links

KEGG Pathway ID	Description
hsa05034	Alcoholism
ko05034	Alcoholism
hsa04024	cAMP signaling pathway
ko04024	cAMP signaling pathway
hsa05030	Cocaine addiction
ko05030	Cocaine addiction
hsa05016	Huntington's disease
ko05016	Huntington's disease
hsa04010	MAPK signaling pathway
ko04010	MAPK signaling pathway
hsa04722	Neurotrophin signaling pathway
ko04722	Neurotrophin signaling pathway