MitoProteome Database

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MT000093

Gene Information

Entrez Gene ID686
Gene Namebiotinidase
Gene SymbolBTD
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0045177 IEA:EnsemblCapical part of cell
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 IDA:UniProtCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005759 TAS:ReactomeCmitochondrial matrix
GO:0005730 IEA:EnsemblCnucleolus
GO:0043204 IEA:EnsemblCperikaryon
GO:0004075 TAS:ProtIncFbiotin carboxylase activity
GO:0047708 IEA:UniProtKB-ECFbiotinidase activity
GO:0006768 TAS:ReactomePbiotin metabolic process
GO:0007417 TAS:ProtIncPcentral nervous system development
GO:0008544 TAS:ProtIncPepidermis development
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006766 TAS:ReactomePvitamin metabolic process
GO:0006767 TAS:ReactomePwater-soluble vitamin metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa00780Biotin metabolism
ko00780Biotin metabolism
hsa01100Metabolic pathways
hsa04977Vitamin digestion and absorption
ko04977Vitamin digestion and absorption
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_11153Biotin transport and metabolism
REACT_169280Defective AMN causes hereditary megaloblastic anemia 1
REACT_169403Defective BTD causes biotidinase deficiency
REACT_169178Defective CD320 causes methylmalonic aciduria
REACT_169132Defective CUBN causes hereditary megaloblastic anemia 1
REACT_169415Defective GIF causes intrinsic factor deficiency
REACT_169312Defective HLCS causes multiple carboxylase deficiency
REACT_169363Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
REACT_169316Defective MMAA causes methylmalonic aciduria type cblA
REACT_169318Defective MMAB causes methylmalonic aciduria type cblB
REACT_169169Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
REACT_169256Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
REACT_169149Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
REACT_169439Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
REACT_169313Defective MUT causes methylmalonic aciduria mut type
REACT_169120Defective TCN2 causes hereditary megaloblastic anemia
REACT_169238Defects in biotin (Btn) metabolism
REACT_169429Defects in cobalamin (B12) metabolism
REACT_169385Defects in vitamin and cofactor metabolism
REACT_116125Disease
REACT_111217Metabolism
REACT_11193Metabolism of vitamins and cofactors
REACT_11238Metabolism of water-soluble vitamins and cofactors