MitoProteome Database

MT000146

Gene Information

Entrez Gene ID	1374
Gene Name	carnitine palmitoyltransferase 1A (liver)
Gene Symbol	CPT1A
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0031307	ISS:UniProtKB	C	integral component of mitochondrial outer membrane
GO:0016020	IDA:UniProtKB	C	membrane
GO:0005743	IEA:Ensembl	C	mitochondrial inner membrane
GO:0005741	TAS:Reactome	C	mitochondrial outer membrane
GO:0005739	IDA:UniProtKB	C	mitochondrion
GO:0004095	IDA:UniProtKB	F	carnitine O-palmitoyltransferase activity
GO:0009437	IDA:UniProtKB	P	carnitine metabolic process
GO:0006853	TAS:Reactome	P	carnitine shuttle
GO:0044255	TAS:Reactome	P	cellular lipid metabolic process
GO:0071398	IEA:Ensembl	P	cellular response to fatty acid
GO:0042755	IEA:Ensembl	P	eating behavior
GO:0030855	IEP:UniProt	P	epithelial cell differentiation
GO:0006635	TAS:ProtInc	P	fatty acid beta-oxidation
GO:0006006	IEA:Ensembl	P	glucose metabolic process
GO:0001676	IDA:UniProtKB	P	long-chain fatty acid metabolic process
GO:0032000	IEA:Ensembl	P	positive regulation of fatty acid beta-oxidation
GO:0051260	IEA:Ensembl	P	protein homooligomerization
GO:0050796	IEA:Ensembl	P	regulation of insulin secretion
GO:0042493	IEA:Ensembl	P	response to drug
GO:0014070	IEA:Ensembl	P	response to organic cyclic compound
GO:0044281	TAS:Reactome	P	small molecule metabolic process
GO:0006641	IEA:Ensembl	P	triglyceride metabolic process

KEGG Pathway Links

KEGG Pathway ID	Description
hsa04920	Adipocytokine signaling pathway
ko04920	Adipocytokine signaling pathway
hsa04152	AMPK signaling pathway
ko04152	AMPK signaling pathway
hsa00071	Fatty acid degradation
ko00071	Fatty acid degradation
hsa01212	Fatty acid metabolism
ko01212	Fatty acid metabolism
hsa03320	PPAR signaling pathway
ko03320	PPAR signaling pathway

BIOCYC Pathway Links

BIOCYC Pathway ID	Description
PWY-6111	mitochondrial L-carnitine shuttle
PWY-6111	mitochondrial L-carnitine shuttle pathway

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_24941	Circadian Clock
REACT_22279	Fatty acid, triacylglycerol, and ketone body metabolism
REACT_11082	Import of palmitoyl-CoA into the mitochondrial matrix
REACT_111217	Metabolism
REACT_22258	Metabolism of lipids and lipoproteins
REACT_116145	PPARA activates gene expression
REACT_19241	Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
REACT_118659	RORA activates circadian gene expression