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MT000154

UniProt Annotations

Entry Information

Gene Name	citrate synthase
Protein Entry	CISY_HUMAN
UniProt ID	O75390
Species	Human

Comments

Comment type	Description
Catalytic Activity	Acetyl-CoA + H(2)O + oxaloacetate = citrate + CoA. {ECO:0000255\|PROSITE-ProRule:PRU10117}.
Miscellaneous	Citrate synthase is found in nearly all cells capable of oxidative metabolism.
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 1/2.
Sequence Caution	Sequence=CAE45911.1; Type=Miscellaneous discrepancy; Note=Intron retention.; Evidence={ECO:0000305};
Similarity	Belongs to the citrate synthase family. {ECO:0000305}.
Subcellular Location	Mitochondrion matrix.
Subunit	Homodimer. {ECO:0000250}.
Web Resource	Name=Wikipedia; Note=Citrate synthase entry; URL="http://en.wikipedia.org/wiki/Citrate_synthase";