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MT000159

Record overview

MITO ID	MT000159
Gene ID	1528
Species	Homo sapiens (Human)
Gene Name	cytochrome b5 type A (microsomal)
Gene Symbol	CYB5A
Synonyms	CYB5; MCB5;
Alternate names	cytochrome b5; type 1 cyt-b5;
Chromosome	18
Map Location	18q23
Summary	The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Orthologs	View orthologs and multiple alignments for CYB5A

Proteins

cytochrome b5 isoform 1

Refseq ID:	NP_683725
Protein GI:	41281768
UniProt ID:	P00167
mRNA ID:	NM_148923
Length:	134
RefSeq Status:

cytochrome b5 isoform 2
`MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKPPETLI TTIDSSSSWWTNWVIPAISAVAVALMYRLYMAED`

Refseq ID:	NP_001905
Protein GI:	4503183
UniProt ID:	P00167
mRNA ID:	NM_001914
Length:	98
RefSeq Status:

cytochrome b5 isoform 3
`MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKPPEP`

Refseq ID:	NP_001177736
Protein GI:	299829246
UniProt ID:	P00167
mRNA ID:	NM_001190807
Length:	124
RefSeq Status:

`MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHSTDAREMSKTFIIGELHPETLITTIDSSSSWW TNWVIPAISAVAVALMYRLYMAED`