MitoProteome Database

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MT000169

Gene Information

Entrez Gene ID1585
Gene Namecytochrome P450, family 11, subfamily B, polypeptide 2
Gene SymbolCYP11B2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005743 IC:BHF-UCLCmitochondrial inner membrane
GO:0005739 IDA:BHF-UCLCmitochondrion
GO:0047783 IEA:UniProtKB-ECFcorticosterone 18-monooxygenase activity
GO:0020037 IDA:UniProtKBFheme binding
GO:0005506 IEA:InterProFiron ion binding
GO:0004507 IDA:UniProtKBFsteroid 11-beta-monooxygenase activity
GO:0032342 IDA:UniProtKBPaldosterone biosynthetic process
GO:0006700 IDA:BHF-UCLPC21-steroid hormone biosynthetic process
GO:0032870 IEP:UniProtKBPcellular response to hormone stimulus
GO:0035865 IEP:UniProtKBPcellular response to potassium ion
GO:0034651 IMP:UniProtKBPcortisol biosynthetic process
GO:0006705 TAS:ReactomePmineralocorticoid biosynthetic process
GO:0055075 IMP:BHF-UCLPpotassium ion homeostasis
GO:0002017 IMP:BHF-UCLPregulation of blood volume by renal aldosterone
GO:0003091 IC:BHF-UCLPrenal water homeostasis
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0055078 IMP:BHF-UCLPsodium ion homeostasis
GO:0008202 TAS:ReactomePsteroid metabolic process
GO:0016125 TAS:ReactomePsterol metabolic process
GO:0006805 TAS:ReactomePxenobiotic metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa_M00108C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone
M00108C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone
hsa_M00109C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
M00109C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
hsa01100Metabolic pathways
hsa00140Steroid hormone biosynthesis
ko00140Steroid hormone biosynthesis
BIOCYC Pathway Links
BIOCYC Pathway IDDescription
PWY66-382mineralocorticoid biosynthesis
PWY66-382mineralocorticoid biosynthesis
PWY-7305superpathway of steroid hormone biosynthesis
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_13433Biological oxidations
REACT_13567Cytochrome P450 - arranged by substrate type
REACT_13812Endogenous sterols
REACT_11036Glucocorticoid biosynthesis
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_11057Metabolism of steroid hormones and vitamin D
REACT_11047Mineralocorticoid biosynthesis
REACT_13705Phase 1 - Functionalization of compounds