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MitoProteome Human Mitochondrial Protein Database
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Related Proteins
MT000173
Gene Information
Entrez Gene ID
1594
Gene Name
cytochrome P450, family 27, subfamily B, polypeptide 1
Gene Symbol
CYP27B1
Species
Homo sapiens
Gene Ontology (GO Annotations)
GO ID
Source
Type
Description
GO:0005737
IDA:BHF-UCL
C
cytoplasm
GO:0005741
TAS:Reactome
C
mitochondrial outer membrane
GO:0005739
ISS:BHF-UCL
C
mitochondrion
GO:0004498
IDA:BHF-UCL
F
calcidiol 1-monooxygenase activity
GO:0020037
IEA:InterPro
F
heme binding
GO:0005506
IEA:InterPro
F
iron ion binding
GO:0030282
IEP:BHF-UCL
P
bone mineralization
GO:0036378
IDA:BHF-UCL
P
calcitriol biosynthetic process from calciol
GO:0055074
IMP:BHF-UCL
P
calcium ion homeostasis
GO:0006816
ISS:BHF-UCL
P
calcium ion transport
GO:0046697
IEP:BHF-UCL
P
decidualization
GO:0070314
IMP:BHF-UCL
P
G1 to G0 transition
GO:0010956
IDA:BHF-UCL
P
negative regulation of calcidiol 1-monooxygenase activity
GO:0030308
IMP:BHF-UCL
P
negative regulation of cell growth
GO:0008285
IDA:BHF-UCL
P
negative regulation of cell proliferation
GO:0045618
IMP:BHF-UCL
P
positive regulation of keratinocyte differentiation
GO:0010980
IDA:BHF-UCL
P
positive regulation of vitamin D 24-hydroxylase activity
GO:0070564
IDA:BHF-UCL
P
positive regulation of vitamin D receptor signaling pathway
GO:0030500
IMP:BHF-UCL
P
regulation of bone mineralization
GO:0043627
IEP:BHF-UCL
P
response to estrogen
GO:0034341
IDA:BHF-UCL
P
response to interferon-gamma
GO:0032496
IDA:BHF-UCL
P
response to lipopolysaccharide
GO:0033280
IDA:BHF-UCL
P
response to vitamin D
GO:0044281
TAS:Reactome
P
small molecule metabolic process
GO:0008202
TAS:Reactome
P
steroid metabolic process
GO:0042369
IEA:Ensembl
P
vitamin D catabolic process
GO:0042359
IDA:BHF-UCL
P
vitamin D metabolic process
GO:0006766
TAS:Reactome
P
vitamin metabolic process
GO:0006805
TAS:Reactome
P
xenobiotic metabolic process
KEGG Pathway Links
KEGG Pathway ID
Description
hsa_M00103
Cholecalciferol biosynthesis
M00103
Cholecalciferol biosynthesis
hsa01100
Metabolic pathways
hsa00100
Steroid biosynthesis
ko00100
Steroid biosynthesis
hsa05152
Tuberculosis
ko05152
Tuberculosis
BIOCYC Pathway Links
BIOCYC Pathway ID
Description
PWY-6076
1,25-dihydroxyvitamin D3 biosynthesis
REACTOME Pathway Links
REACTOME Pathway ID
Description
REACT_13433
Biological oxidations
REACT_13567
Cytochrome P450 - arranged by substrate type
REACT_111217
Metabolism
REACT_22258
Metabolism of lipids and lipoproteins
REACT_11057
Metabolism of steroid hormones and vitamin D
REACT_13705
Phase 1 - Functionalization of compounds
REACT_13523
Vitamin D (calciferol) metabolism
REACT_13450
Vitamins
MitoProteome Human Mitochondrial Protein Database
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