MitoProteome Database

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MT000183

Gene Information

Entrez Gene ID1727
Gene Namecytochrome b5 reductase 3
Gene SymbolCYB5R3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 TAS:ProtIncCcytoplasm
GO:0005783 IDA:HPACendoplasmic reticulum
GO:0005789 IEA:EnsemblCendoplasmic reticulum membrane
GO:0070062 IDA:UniProtCextracellular vesicular exosome
GO:0005833 TAS:ProtIncChemoglobin complex
GO:0005811 IDA:UniProtKBClipid particle
GO:0016020 IDA:UniProtKBCmembrane
GO:0005743 IEA:EnsemblCmitochondrial inner membrane
GO:0005741 TAS:ReactomeCmitochondrial outer membrane
GO:0005739 IDA:UniProtCmitochondrion
GO:0043531 IEA:EnsemblFADP binding
GO:0016208 IEA:EnsemblFAMP binding
GO:0004128 TAS:ReactomeFcytochrome-b5 reductase activity, acting on NAD(P)H
GO:0071949 IDA:UniProtKBFFAD binding
GO:0050660 IEA:EnsemblFflavin adenine dinucleotide binding
GO:0051287 IEA:EnsemblFNAD binding
GO:0008015 TAS:ProtIncPblood circulation
GO:0006695 IEA:UniProtKB-KWPcholesterol biosynthetic process
GO:0019852 TAS:ReactomePL-ascorbic acid metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006766 TAS:ReactomePvitamin metabolic process
GO:0006767 TAS:ReactomePwater-soluble vitamin metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa00520Amino sugar and nucleotide sugar metabolism
ko00520Amino sugar and nucleotide sugar metabolism
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_169280Defective AMN causes hereditary megaloblastic anemia 1
REACT_169403Defective BTD causes biotidinase deficiency
REACT_169178Defective CD320 causes methylmalonic aciduria
REACT_169132Defective CUBN causes hereditary megaloblastic anemia 1
REACT_169415Defective GIF causes intrinsic factor deficiency
REACT_169312Defective HLCS causes multiple carboxylase deficiency
REACT_169363Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
REACT_169316Defective MMAA causes methylmalonic aciduria type cblA
REACT_169318Defective MMAB causes methylmalonic aciduria type cblB
REACT_169169Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
REACT_169256Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
REACT_169149Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
REACT_169439Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
REACT_169313Defective MUT causes methylmalonic aciduria mut type
REACT_169120Defective TCN2 causes hereditary megaloblastic anemia
REACT_169238Defects in biotin (Btn) metabolism
REACT_169429Defects in cobalamin (B12) metabolism
REACT_169385Defects in vitamin and cofactor metabolism
REACT_116125Disease
REACT_111217Metabolism
REACT_11193Metabolism of vitamins and cofactors
REACT_11238Metabolism of water-soluble vitamins and cofactors
REACT_11202Vitamin C (ascorbate) metabolism