MitoProteome Database

MT000185

Gene Information

Entrez Gene ID1737
Gene Namedihydrolipoamide S-acetyltransferase
Gene SymbolDLAT
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005759 TAS:ReactomeCmitochondrial matrix
GO:0005967 NAS:UniProtKBCmitochondrial pyruvate dehydrogenase complex
GO:0005739 IDA:UniProtCmitochondrion
GO:0004742 NAS:UniProtKBFdihydrolipoyllysine-residue acetyltransferase activity
GO:0044237 TAS:ReactomePcellular metabolic process
GO:0006006 IEA:UniProtKB-KWPglucose metabolic process
GO:0006090 TAS:ReactomePpyruvate metabolic process
GO:0010510 TAS:ReactomePregulation of acetyl-CoA biosynthetic process from pyruvate
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006099 IEA:UniProtKB-KWPtricarboxylic acid cycle
KEGG Pathway Links
KEGG Pathway IDDescription
hsa01200Carbon metabolism
ko01200Carbon metabolism
hsa00020Citrate cycle (TCA cycle)
ko00020Citrate cycle (TCA cycle)
hsa00010Glycolysis / Gluconeogenesis
ko00010Glycolysis / Gluconeogenesis
hsa01100Metabolic pathways
hsa00620Pyruvate metabolism
ko00620Pyruvate metabolism
hsa_M00307Pyruvate oxidation, pyruvate => acetyl-CoA
M00307Pyruvate oxidation, pyruvate => acetyl-CoA
BIOCYC Pathway Links
BIOCYC Pathway IDDescription
PYRUVDEHYD-PWYpyruvate decarboxylation to acetyl CoA
PYRUVDEHYD-PWYpyruvate decarboxylation to acetyl CoA
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111217Metabolism
REACT_2071Pyruvate metabolism
REACT_1046Pyruvate metabolism and Citric Acid (TCA) cycle
REACT_12528Regulation of pyruvate dehydrogenase (PDH) complex
REACT_111083The citric acid (TCA) cycle and respiratory electron transport