MitoProteome Database

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MT000190

Gene Information

Entrez Gene ID1763
Gene NameDNA replication helicase/nuclease 2
Gene SymbolDNA2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0042645 IDA:UniProtKBCmitochondrial nucleoid
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0005634 IDA:UniProtKBCnucleus
GO:0051539 IEA:UniProtKB-KWF4 iron, 4 sulfur cluster binding
GO:0043139 IDA:UniProtKBF5'-3' DNA helicase activity
GO:0017108 IDA:UniProtKBF5'-flap endonuclease activity
GO:0016887 TAS:UniProtKBFATPase activity
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0003677 IDA:UniProtKBFDNA binding
GO:0003678 IDA:UniProtKBFDNA helicase activity
GO:0004386 TAS:UniProtKBFhelicase activity
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0004518 IDA:UniProtKBFnuclease activity
GO:0043142 IDA:UniProtKBFsingle-stranded DNA-dependent ATPase activity
GO:0016890 IDA:UniProtKBFsite-specific endodeoxyribonuclease activity, specific for altered base
GO:0006200 IDA:GOCPATP catabolic process
GO:0006284 IDA:UniProtKBPbase-excision repair
GO:0000737 IDA:GOCPDNA catabolic process, endonucleolytic
GO:0000729 IDA:UniProtKBPDNA double-strand break processing
GO:0032508 IDA:GOCPDNA duplex unwinding
GO:0006260 IMP:UniProtKBPDNA replication
GO:0000076 IMP:UniProtKBPDNA replication checkpoint
GO:0033567 IDA:UniProtKBPDNA replication, Okazaki fragment processing
GO:0043137 IDA:UniProtKBPDNA replication, removal of RNA primer
GO:0006271 TAS:ReactomePDNA strand elongation involved in DNA replication
GO:0043504 IDA:UniProtKBPmitochondrial DNA repair
GO:0006264 IDA:UniProtKBPmitochondrial DNA replication
GO:0000278 TAS:ReactomePmitotic cell cycle
GO:0045740 IDA:UniProtKBPpositive regulation of DNA replication
GO:0000723 TAS:ReactomePtelomere maintenance
GO:0000722 TAS:ReactomePtelomere maintenance via recombination
GO:0032201 TAS:ReactomePtelomere maintenance via semi-conservative replication
KEGG Pathway Links
KEGG Pathway IDDescription
hsa03030DNA replication
ko03030DNA replication
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_115566Cell Cycle
REACT_152Cell Cycle, Mitotic
REACT_22172Chromosome Maintenance
REACT_383DNA Replication
REACT_932DNA strand elongation
REACT_8030Extension of Telomeres
REACT_312Lagging Strand Synthesis
REACT_8027Processive synthesis on the C-strand of the telomere
REACT_1385Processive synthesis on the lagging strand
REACT_70Removal of the Flap Intermediate
REACT_7999Removal of the Flap Intermediate from the C-strand
REACT_899S Phase
REACT_2014Synthesis of DNA
REACT_7961Telomere C-strand (Lagging Strand) Synthesis
REACT_7970Telomere Maintenance