MitoProteome Database

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MT000192

UniProt Annotations

Entry Information

Gene Name	developmentally regulated GTP binding protein 2
Protein Entry	DRG2_HUMAN
UniProt ID	P55039
Species	Human

Comments

Comment type	Description
Function	May play a role in cell proliferation, differentiation and death.
Ptm	Polyubiquitinated; which induces proteolytic degradation and is impaired by interaction with RWDD1. {ECO:0000250}.
Similarity	Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. {ECO:0000255\|PROSITE- ProRule:PRU01047}.
Similarity	Contains 1 OBG-type G (guanine nucleotide-binding) domain. {ECO:0000255\|PROSITE-ProRule:PRU01047}.
Subcellular Location	Cytoplasm.
Subunit	Interacts with RWDD1. {ECO:0000250}.
Tissue Specificity	Highest levels in skeletal muscle, heart and kidney. Low levels in colon, thymus, spleen, small intestine, lung and Leukocytes.