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MitoProteome Human Mitochondrial Protein Database
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Related Proteins
MT000218
Gene Information
Entrez Gene ID
2182
Gene Name
acyl-CoA synthetase long-chain family member 4
Gene Symbol
ACSL4
Species
Homo sapiens
Gene Ontology (GO Annotations)
GO ID
Source
Type
Description
GO:0005737
IDA:UniProtKB
C
cytoplasm
GO:0005789
TAS:Reactome
C
endoplasmic reticulum membrane
GO:0044233
IDA:MGI
C
ER-mitochondrion membrane contact site
GO:0070062
IDA:UniProt
C
extracellular vesicular exosome
GO:0016021
IEA:UniProtKB-KW
C
integral component of membrane
GO:0005811
IDA:UniProtKB
C
lipid particle
GO:0016020
IDA:UniProtKB
C
membrane
GO:0005741
IEA:UniProtKB-KW
C
mitochondrial outer membrane
GO:0043025
IEA:Ensembl
C
neuronal cell body
GO:0005777
IEA:UniProtKB-KW
C
peroxisome
GO:0047676
IDA:UniProtKB
F
arachidonate-CoA ligase activity
GO:0005524
IEA:UniProtKB-KW
F
ATP binding
GO:0004467
IDA:MGI
F
long-chain fatty acid-CoA ligase activity
GO:0031957
IMP:UniProtKB
F
very long-chain fatty acid-CoA ligase activity
GO:0044255
TAS:Reactome
P
cellular lipid metabolic process
GO:0060996
IEA:Ensembl
P
dendritic spine development
GO:0060136
IEA:Ensembl
P
embryonic process involved in female pregnancy
GO:0015908
IEA:Ensembl
P
fatty acid transport
GO:0008610
IDA:UniProtKB
P
lipid biosynthetic process
GO:0006629
IDA:UniProtKB
P
lipid metabolic process
GO:0001676
IDA:GOC
P
long-chain fatty acid metabolic process
GO:0035338
TAS:Reactome
P
long-chain fatty-acyl-CoA biosynthetic process
GO:0032307
IDA:UniProtKB
P
negative regulation of prostaglandin secretion
GO:0030307
IDA:UniProtKB
P
positive regulation of cell growth
GO:0070672
IEA:Ensembl
P
response to interleukin-15
GO:0007584
IEA:Ensembl
P
response to nutrient
GO:0044281
TAS:Reactome
P
small molecule metabolic process
GO:0019432
TAS:Reactome
P
triglyceride biosynthetic process
KEGG Pathway Links
KEGG Pathway ID
Description
hsa04920
Adipocytokine signaling pathway
ko04920
Adipocytokine signaling pathway
hsa_M00086
beta-Oxidation, acyl-CoA synthesis
M00086
beta-Oxidation, acyl-CoA synthesis
hsa00061
Fatty acid biosynthesis
ko00061
Fatty acid biosynthesis
hsa00071
Fatty acid degradation
ko00071
Fatty acid degradation
hsa01212
Fatty acid metabolism
ko01212
Fatty acid metabolism
hsa01100
Metabolic pathways
hsa04146
Peroxisome
ko04146
Peroxisome
hsa03320
PPAR signaling pathway
ko03320
PPAR signaling pathway
REACTOME Pathway Links
REACTOME Pathway ID
Description
REACT_22279
Fatty acid, triacylglycerol, and ketone body metabolism
REACT_1319
Fatty Acyl-CoA Biosynthesis
REACT_111217
Metabolism
REACT_22258
Metabolism of lipids and lipoproteins
REACT_380
Synthesis of very long-chain fatty acyl-CoAs
REACT_1190
Triglyceride Biosynthesis
MitoProteome Human Mitochondrial Protein Database
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