MitoProteome Database

MT000359

Gene Information

Entrez Gene ID	4287
Gene Name	ataxin 3
Gene Symbol	ATXN3
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	TAS:ProtInc	C	cytoplasm
GO:0005829	IDA:ParkinsonsUK-UCL	C	cytosol
GO:0005654	TAS:ProtInc	C	nucleoplasm
GO:0005634	IDA:ParkinsonsUK-UCL	C	nucleus
GO:0051117	IPI:ParkinsonsUK-UCL	F	ATPase binding
GO:0042802	IPI:IntAct	F	identical protein binding
GO:1990380	IDA:ParkinsonsUK-UCL	F	Lys48-specific deubiquitinase activity
GO:0061578	IDA:ParkinsonsUK-UCL	F	Lys63-specific deubiquitinase activity
GO:0008242	IEA:InterPro	F	omega peptidase activity
GO:0031625	ISS:UniProtKB	F	ubiquitin protein ligase binding
GO:0004843	ISS:UniProtKB	F	ubiquitin-specific protease activity
GO:0004221	ISS:UniProtKB	F	ubiquitin thiolesterase activity
GO:0030036	IMP:MGI	P	actin cytoskeleton organization
GO:0008219	IEA:UniProtKB-KW	P	cell death
GO:0071218	ISS:UniProtKB	P	cellular response to misfolded protein
GO:0045104	IMP:MGI	P	intermediate filament cytoskeleton organization
GO:0000226	IMP:MGI	P	microtubule cytoskeleton organization
GO:0006515	ISS:UniProtKB	P	misfolded or incompletely synthesized protein catabolic process
GO:0035520	ISS:UniProtKB	P	monoubiquitinated protein deubiquitination
GO:0007399	TAS:ProtInc	P	nervous system development
GO:0006289	TAS:ProtInc	P	nucleotide-excision repair
GO:0043161	ISS:UniProtKB	P	proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0071108	IDA:ParkinsonsUK-UCL	P	protein K48-linked deubiquitination
GO:0070536	IDA:ParkinsonsUK-UCL	P	protein K63-linked deubiquitination
GO:0010810	IMP:MGI	P	regulation of cell-substrate adhesion
GO:0006355	IEA:UniProtKB-KW	P	regulation of transcription, DNA-templated
GO:0007268	TAS:ProtInc	P	synaptic transmission
GO:0006351	IEA:UniProtKB-KW	P	transcription, DNA-templated

KEGG Pathway Links

KEGG Pathway ID	Description
hsa04141	Protein processing in endoplasmic reticulum
ko04141	Protein processing in endoplasmic reticulum