MitoProteome Database

MT000650

Record overview

MITO ID	MT000650
Gene ID	8209
Species	Homo sapiens (Human)
Gene Name	chromosome 21 open reading frame 33
Gene Symbol	C21orf33
Synonyms	ES1; HES1; KNPH; KNPI; GT335;
Alternate names	ES1 protein homolog, mitochondrial; Keio novel protein I; human HES1 protein, homolog to E.coli and zebrafish ES1 protein;
Chromosome	21
Map Location	21q22.3
Summary	This gene encodes a potential mitochondrial protein that is a member of the DJ-1/PfpI gene family. This protein is overexpressed in fetal Down syndrome brain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Orthologs	View orthologs and multiple alignments for C21orf33

Proteins

ES1 protein homolog, mitochondrial isoform Ia precursor

Refseq ID:	NP_004640
Protein GI:	296531406
UniProt ID:	P30042
mRNA ID:	NM_004649
Length:	268
RefSeq Status:

`MAAVRALVASRLAAASAFTSLSPGGRTPSQRAALHLSVPRPAARVALVLSGCGVYDGTEIHEASAILVHLSRGGAEVQIFAPDVPQMHVIDHTKGQPSEG ESRNVLTESARIARGKITDLANLSAANHDAAIFPGGFGAAKNLSTFAVDGKDCKVNKEVERVLKEFHQAGKPIGLCCIAPVLAAKVLRGVEVTVGHEQEE GGKWPYAGTAEAIKALGAKHCVKEVVEAHVDQKNKVVTTPAFMCETALHYIHDGIGAMVRKVLELTGK`

N
transit_peptide: 1..41
calculated_mol_wt: 4144
peptide sequence: 
MAAVRALVASRLAAASAFTSLSPGGRTPSQRAALHLSVPRP

mat_peptide: 42..237
product: ES1 protein homolog, mitochondrial isoform Ib
calculated_mol_wt: 20604
peptide sequence: 
AARVALVLSGCGVYDGTEIHEASAILVHLSRGGAEVQIFAPDVPQMHVIDHTKGQPSEGESRNVLTESARIARGKITDLANLSAANHDAAIFPGGFGAAK
NLLCCIAPVLAAKVLRGVEVTVGHEQEEGGKWPYAGTAEAIKALGAKHCVKEVVEAHVDQKNKVVTTPAFMCETALHYIHDGIGAMVRKVLELTGK

transit_peptide: 1..41
calculated_mol_wt: 4144
peptide sequence: 
MAAVRALVASRLAAASAFTSLSPGGRTPSQRAALHLSVPRP

mat_peptide: 42..268
product: ES1 protein homolog, mitochondrial isoform Ia
calculated_mol_wt: 24017
peptide sequence: 
AARVALVLSGCGVYDGTEIHEASAILVHLSRGGAEVQIFAPDVPQMHVIDHTKGQPSEGESRNVLTESARIARGKITDLANLSAANHDAAIFPGGFGAAK
NLSTFAVDGKDCKVNKEVERVLKEFHQAGKPIGLCCIAPVLAAKVLRGVEVTVGHEQEEGGKWPYAGTAEAIKALGAKHCVKEVVEAHVDQKNKVVTTPA
FMCETALHYIHDGIGAMVRKVLELTGK

ES1 protein homolog, mitochondrial isoform Ib precursor

Refseq ID:	NP_937798
Protein GI:	296531408
UniProt ID:	P30042
mRNA ID:	NM_198155
Length:	237
RefSeq Status:

`MAAVRALVASRLAAASAFTSLSPGGRTPSQRAALHLSVPRPAARVALVLSGCGVYDGTEIHEASAILVHLSRGGAEVQIFAPDVPQMHVIDHTKGQPSEG ESRNVLTESARIARGKITDLANLSAANHDAAIFPGGFGAAKNLLCCIAPVLAAKVLRGVEVTVGHEQEEGGKWPYAGTAEAIKALGAKHCVKEVVEAHVD QKNKVVTTPAFMCETALHYIHDGIGAMVRKVLELTGK`

N
transit_peptide: 1..41
calculated_mol_wt: 4144
peptide sequence: 
MAAVRALVASRLAAASAFTSLSPGGRTPSQRAALHLSVPRP

mat_peptide: 42..237
product: ES1 protein homolog, mitochondrial isoform Ib
calculated_mol_wt: 20604
peptide sequence: 
AARVALVLSGCGVYDGTEIHEASAILVHLSRGGAEVQIFAPDVPQMHVIDHTKGQPSEGESRNVLTESARIARGKITDLANLSAANHDAAIFPGGFGAAK
NLLCCIAPVLAAKVLRGVEVTVGHEQEEGGKWPYAGTAEAIKALGAKHCVKEVVEAHVDQKNKVVTTPAFMCETALHYIHDGIGAMVRKVLELTGK