MitoProteome Database

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MT000683

UniProt Annotations

Entry Information

Gene Name	DDB1 and CUL4 associated factor 5
Protein Entry	DCAF5_HUMAN
UniProt ID	Q96JK2
Species	Human

Comments

Comment type	Description
Alternative Products	Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q96JK2-1; Sequence=Displayed; Name=2; IsoId=Q96JK2-2; Sequence=VSP_010386; Note=No experimental confirmation available.; Name=3; IsoId=Q96JK2-3; Sequence=VSP_055647; Note=No experimental confirmation available. Gene prediction based on cDNA data.;
Function	May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. {ECO:0000269\|PubMed:16949367, ECO:0000269\|PubMed:16964240}.
Pathway	Protein modification; protein ubiquitination.
Sequence Caution	Sequence=AAC08965.1; Type=Frameshift; Positions=772, 809, 812, 817, 836, 844, 858; Evidence={ECO:0000305}; Sequence=BAB47453.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Similarity	Contains 6 WD repeats. {ECO:0000255\|PROSITE- ProRule:PRU00221}.
Subunit	Interacts with DDB1 and CUL4A. {ECO:0000269\|PubMed:16949367}.
Tissue Specificity	Ubiquitous. {ECO:0000269\|PubMed:9740667}.