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MT000685

Record overview

MITO IDMT000685
Gene ID8846
SpeciesHomo sapiens (Human)
Gene NamealkB, alkylation repair homolog 1 (E. coli)
Gene SymbolALKBH1
SynonymsABH; ABH1; alkB; hABH; ALKBH;
Alternate namesalkylated DNA repair protein alkB homolog 1; DNA lyase ABH1; alkylation repair, alkB homolog; DNA oxidative demethylase ALKBH1; alpha-ketoglutarate-dependent dioxygenase ABH1;
Chromosome14
Map Location14q24.3
EC Number1.14.11.33
SummaryThis gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for ALKBH1

Proteins

alkylated DNA repair protein alkB homolog 1
Refseq ID:NP_006011
Protein GI:87298840
UniProt ID:Q13686
mRNA ID:NM_006020
Length:389
RefSeq Status:
MGKMAAAVGSVATLATEPGEDAFRKLFRFYRQSRPGTADLEGVIDFSAAHAARGKGPGAQKVIKSQLNVSSVSEQNAYRAGLQPVSKWQAYGLKGYPGFI
FIPNPFLPGYQWHWVKQCLKLYSQKPNVCNLDKHMSKEETQDLWEQSKEFLRYKEATKRRPRSLLEKLRWVTVGYHYNWDSKKYSADHYTPFPSDLGFLS
EQVAAACGFEDFRAEAGILNYYRLDSTLGIHVDRSELDHSKPLLSFSFGQSAIFLLGGLQRDEAPTAMFMHSGDIMIMSGFSRLLNHAVPRVLPNPEGEG
LPHCLEAPLPAVLPRDSMVEPCSMEDWQVCASYLKTARVNMTVRQVLATDQNFPLEPIEDEKRDISTEGFCHLDDQNSEVKRARINPDS