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MT000693

Record overview

MITO IDMT000693
Gene ID9049
SpeciesHomo sapiens (Human)
Gene Namearyl hydrocarbon receptor interacting protein
Gene SymbolAIP
SynonymsARA9; XAP2; XAP-2; FKBP16; FKBP37; SMTPHN;
Alternate namesAH receptor-interacting protein; immunophilin homolog ARA9; HBV X-associated protein 2;
Chromosome11
Map Location11q13.3
SummaryThe protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]
OrthologsView orthologs and multiple alignments for AIP

Proteins

AH receptor-interacting protein isoform 1
Refseq ID:NP_003968
Protein GI:729042247
UniProt ID:
mRNA ID:NM_003977
Length:330
RefSeq Status:
MADIIARLREDGIQKRVIQEGRGELPDFQDGTKATFHYRTLHSDDEGTVLDDSRARGKPMELIIGKKFKLPVWETIVCTMREGEIAQFLCDIKHVVLYPL
VAKSLRNIAVGKDPLEGQRHCCGVAQMREHSSLGHADLDALQQNPQPLIFHMEMLKVESPGTYQQDPWAMTDEEKAKAVPLIHQEGNRLYREGHVKEAAA
KYYDAIACLKNLQMKEQPGSPEWIQLDQQITPLLLNYCQCKLVVEEYYEVLDHCSSILNKYDDNVKAYFKRGKAHAAVWNAQEAQADFAKVLELDPALAP
VVSRELRALEARIRQKDEEDKARFRGIFSH
 
AH receptor-interacting protein isoform 2
Refseq ID:NP_001289888
Protein GI:729042249
UniProt ID:
mRNA ID:NM_001302959
Length:271
RefSeq Status:
MELIIGKKFKLPVWETIVCTMREGEIAQFLCDIKHVVLYPLVAKSLRNIAVGKDPLEGQRHCCGVAQMREHSSLGHADLDALQQNPQPLIFHMEMLKVES
PGTYQQDPWAMTDEEKAKAVPLIHQEGNRLYREGHVKEAAAKYYDAIACLKNLQMKEQPGSPEWIQLDQQITPLLLNYCQCKLVVEEYYEVLDHCSSILN
KYDDNVKAYFKRGKAHAAVWNAQEAQADFAKVLELDPALAPVVSRELRALEARIRQKDEEDKARFRGIFSH
 
AH receptor-interacting protein isoform 3
Refseq ID:NP_001289889
Protein GI:729042251
UniProt ID:
mRNA ID:NM_001302960
Length:283
RefSeq Status:
MADIIARLREDGIQKRVIQEGRGELPDFQDGTKATFHYRTLHSDDEGTVLDDSRARGKPMELIIGKKFKLPVWETIVCTMREGEIAQFLCDIKHVVLYPL
VAKSLRNIAVGKDPLEGQRHCCGVAQMREHSSLGHADLDALQQNPQPLIFHMEMLKVESPGTYQQDPWAMTDEEKAKAVPLIHQEGNRLYREGHVKEAAA
KYYDAIACLKNLQMKEQPGSPEWIQLDQQITPLLLNYCQCKLVVEEYYEVLDHCSSILNKQRQGLLQAGQGPRGRVECPGGPG