MitoProteome Database

MT000696

Gene Information

Entrez Gene ID	9131
Gene Name	apoptosis-inducing factor, mitochondrion-associated, 1
Gene Symbol	AIFM1
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005829	ISS:UniProtKB	C	cytosol
GO:0005743	TAS:UniProtKB	C	mitochondrial inner membrane
GO:0005758	IDA:UniProtKB	C	mitochondrial intermembrane space
GO:0005739	IDA:UniProt	C	mitochondrion
GO:0005634	IDA:UniProtKB	C	nucleus
GO:0003677	IEA:UniProtKB-KW	F	DNA binding
GO:0009055	TAS:ProtInc	F	electron carrier activity
GO:0071949	IEA:Ensembl	F	FAD binding
GO:0016174	TAS:UniProtKB	F	NAD(P)H oxidase activity
GO:0016651	IDA:UniProtKB	F	oxidoreductase activity, acting on NAD(P)H
GO:0006919	IDA:UniProtKB	P	activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006309	TAS:ProtInc	P	apoptotic DNA fragmentation
GO:0006915	IMP:UniProtKB	P	apoptotic process
GO:0045454	IEA:InterPro	P	cell redox homeostasis
GO:0030261	TAS:UniProtKB	P	chromosome condensation
GO:0006308	TAS:UniProtKB	P	DNA catabolic process
GO:0070059	ISS:UniProtKB	P	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0032981	IMP:UniProtKB	P	mitochondrial respiratory chain complex I assembly
GO:0051402	IEA:Ensembl	P	neuron apoptotic process
GO:0030182	IDA:UniProtKB	P	neuron differentiation
GO:0043065	TAS:UniProtKB	P	positive regulation of apoptotic process
GO:1902510	IEA:Ensembl	P	regulation of apoptotic DNA fragmentation

KEGG Pathway Links

KEGG Pathway ID	Description
hsa04210	Apoptosis
ko04210	Apoptosis