MitoProteome Database

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MT000741

Gene Information

Entrez Gene ID10000
Gene Namev-akt murine thymoma viral oncogene homolog 3
Gene SymbolAKT3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0005794 IDA:HPACGolgi apparatus
GO:0005634 IDA:HPACnucleus
GO:0005886 IDA:HPACplasma membrane
GO:0005524 IDA:UniProtKBFATP binding
GO:0004672 TAS:ProtIncFprotein kinase activity
GO:0004674 IDA:UniProtKBFprotein serine/threonine kinase activity
GO:0000002 IMP:UniProtKBPmitochondrial genome maintenance
GO:0006468 TAS:ProtIncPprotein phosphorylation
GO:0007165 IMP:UniProtKBPsignal transduction
KEGG Pathway Links
KEGG Pathway IDDescription
hsa05221Acute myeloid leukemia
ko05221Acute myeloid leukemia
hsa04920Adipocytokine signaling pathway
ko04920Adipocytokine signaling pathway
hsa04261Adrenergic signaling in cardiomyocytes
ko04261Adrenergic signaling in cardiomyocytes
hsa04152AMPK signaling pathway
ko04152AMPK signaling pathway
hsa04210Apoptosis
ko04210Apoptosis
hsa04662B cell receptor signaling pathway
ko04662B cell receptor signaling pathway
hsa04024cAMP signaling pathway
ko04024cAMP signaling pathway
hsa04973Carbohydrate digestion and absorption
ko04973Carbohydrate digestion and absorption
hsa04022cGMP-PKG signaling pathway
ko04022cGMP-PKG signaling pathway
hsa05142Chagas disease (American trypanosomiasis)
ko05142Chagas disease (American trypanosomiasis)
hsa04062Chemokine signaling pathway
ko04062Chemokine signaling pathway
hsa04725Cholinergic synapse
hsa05220Chronic myeloid leukemia
ko05220Chronic myeloid leukemia
hsa05210Colorectal cancer
ko05210Colorectal cancer
hsa04728Dopaminergic synapse
ko04728Dopaminergic synapse
hsa05213Endometrial cancer
ko05213Endometrial cancer
hsa05169Epstein-Barr virus infection
ko05169Epstein-Barr virus infection
hsa04012ErbB signaling pathway
ko04012ErbB signaling pathway
hsa04915Estrogen signaling pathway
ko04915Estrogen signaling pathway
hsa04664Fc epsilon RI signaling pathway
ko04664Fc epsilon RI signaling pathway
hsa04666Fc gamma R-mediated phagocytosis
ko04666Fc gamma R-mediated phagocytosis
hsa04510Focal adhesion
ko04510Focal adhesion
hsa04068FoxO signaling pathway
hsa05214Glioma
ko05214Glioma
hsa05161Hepatitis B
hsa05160Hepatitis C
ko05160Hepatitis C
hsa04066HIF-1 signaling pathway
hsa05166HTLV-I infection
ko05166HTLV-I infection
hsa05164Influenza A
ko05164Influenza A
hsa04910Insulin signaling pathway
ko04910Insulin signaling pathway
hsa04630Jak-STAT signaling pathway
ko04630Jak-STAT signaling pathway
hsa04010MAPK signaling pathway
ko04010MAPK signaling pathway
hsa05162Measles
ko05162Measles
hsa05218Melanoma
ko05218Melanoma
hsa04150mTOR signaling pathway
ko04150mTOR signaling pathway
hsa04722Neurotrophin signaling pathway
ko04722Neurotrophin signaling pathway
hsa04932Non-alcoholic fatty liver disease (NAFLD)
ko04932Non-alcoholic fatty liver disease (NAFLD)
hsa05223Non-small cell lung cancer
ko05223Non-small cell lung cancer
hsa04380Osteoclast differentiation
ko04380Osteoclast differentiation
hsa05212Pancreatic cancer
ko05212Pancreatic cancer
hsa05200Pathways in cancer
hsa04151PI3K-Akt signaling pathway
ko04151PI3K-Akt signaling pathway
hsa04611Platelet activation
hsa04914Progesterone-mediated oocyte maturation
ko04914Progesterone-mediated oocyte maturation
hsa04917Prolactin signaling pathway
ko04917Prolactin signaling pathway
hsa05215Prostate cancer
ko05215Prostate cancer
hsa05205Proteoglycans in cancer
ko05205Proteoglycans in cancer
hsa04015Rap1 signaling pathway
ko04015Rap1 signaling pathway
hsa04014Ras signaling pathway
hsa05211Renal cell carcinoma
ko05211Renal cell carcinoma
hsa04550Signaling pathways regulating pluripotency of stem cells
ko04550Signaling pathways regulating pluripotency of stem cells
hsa05222Small cell lung cancer
ko05222Small cell lung cancer
hsa04660T cell receptor signaling pathway
ko04660T cell receptor signaling pathway
hsa04919Thyroid hormone signaling pathway
hsa04530Tight junction
ko04530Tight junction
hsa04668TNF signaling pathway
ko04668TNF signaling pathway
hsa04620Toll-like receptor signaling pathway
ko04620Toll-like receptor signaling pathway
hsa05145Toxoplasmosis
ko05145Toxoplasmosis
hsa05152Tuberculosis
ko05152Tuberculosis
hsa04370VEGF signaling pathway
ko04370VEGF signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_549Activation of BAD and translocation to mitochondria
REACT_697Activation of BH3-only proteins
REACT_75774Adaptive Immune System
REACT_13655AKT-mediated inactivation of FOXO1A
REACT_12564AKT phosphorylates targets in the cytosol
REACT_12442AKT phosphorylates targets in the nucleus
REACT_578Apoptosis
REACT_19183CD28 co-stimulation
REACT_19358CD28 dependent PI3K/Akt signaling
REACT_147727Constitutive PI3K/AKT Signaling in Cancer
REACT_19344Costimulation by the CD28 family
REACT_19405CTLA4 inhibitory signaling
REACT_147694DAP12 interactions
REACT_147814DAP12 signaling
REACT_111045Developmental Biology
REACT_116125Disease
REACT_115662Downregulation of ERBB2:ERBB3 signaling
REACT_118638Downstream signaling events of B Cell Receptor (BCR)
REACT_21272Downstream signaling of activated FGFR
REACT_17025Downstream signal transduction
REACT_163936Fc epsilon receptor (FCERI) signaling
REACT_12578GAB1 signalosome
REACT_19290G beta:gamma signalling through PI3Kgamma
REACT_19184GPCR downstream signaling
REACT_19388G-protein beta:gamma signalling
REACT_1695GPVI-mediated activation cascade
REACT_604Hemostasis
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_964Intrinsic Pathway for Apoptosis
REACT_12447Negative regulation of the PI3K/AKT network
REACT_12056NGF signalling via TRKA from the plasma membrane
REACT_12464PI3K/AKT activation
REACT_147723PI3K/AKT Signaling in Cancer
REACT_21270PI-3K cascade
REACT_116008PI3K events in ERBB2 signaling
REACT_115961PI3K events in ERBB4 signaling
REACT_75829PIP3 activates AKT signaling
REACT_798Platelet activation, signaling and aggregation
REACT_13698Regulation of beta-cell development
REACT_13819Regulation of gene expression in beta cells
REACT_163769Role of LAT2/NTAL/LAB on calcium mobilization
REACT_9417Signaling by EGFR
REACT_115871Signaling by EGFR in Cancer
REACT_115755Signaling by ERBB2
REACT_115596Signaling by ERBB4
REACT_9470Signaling by FGFR
REACT_120736Signaling by FGFR in disease
REACT_14797Signaling by GPCR
REACT_16888Signaling by PDGF
REACT_111040Signaling by SCF-KIT
REACT_118773Signaling by the B Cell Receptor (BCR)
REACT_12529Signaling by VEGF
REACT_11061Signalling by NGF
REACT_111102Signal Transduction
REACT_228166VEGFA-VEGFR2 Pathway
REACT_228016VEGFR2 mediated vascular permeability