MitoProteome Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MT000754

Record overview

MITO IDMT000754
Gene ID10134
SpeciesHomo sapiens (Human)
Gene NameB-cell receptor-associated protein 31
Gene SymbolBCAP31
SynonymsCDM; DDCH; BAP31; 6C6-AG; DXS1357E;
Alternate namesB-cell receptor-associated protein 31; p28 Bap31; BCR-associated protein Bap31; 6C6-AG tumor-associated antigen;
ChromosomeX
Map LocationXq28
SummaryThis gene encodes a member of the B-cell receptor associated protein 31 superfamily. The encoded protein is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in caspase 8-mediated apoptosis. Microdeletions in this gene are associated with contiguous ABCD1/DXS1375E deletion syndrome (CADDS), a neonatal disorder. Alternative splicing of this gene results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 16. [provided by RefSeq, Jan 2012]
OrthologsView orthologs and multiple alignments for BCAP31

Proteins

B-cell receptor-associated protein 31 isoform a
Refseq ID:NP_001132929
Protein GI:213511508
UniProt ID:P51572
mRNA ID:NM_001139457
Length:313
RefSeq Status:
MGAEASSSWCPGTALPEERLSVKRASEISGFLGQGSSGEAALDVLTHVLEGAGNKLTSSCGKPSSNRMSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQ
KIFKSRLVELLVSYGNTFFVVLIVILVLLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLVTLISQQATLLASN
EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKL
QAAVDGPMDKKEE
 
B-cell receptor-associated protein 31 isoform b
Refseq ID:NP_001132913
Protein GI:213511012
UniProt ID:P51572
mRNA ID:NM_001139441
Length:246
RefSeq Status:
MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILVLLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQ
RNLYIAGFSLLLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELASTKQ
KLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKKEE
 
B-cell receptor-associated protein 31 isoform b
Refseq ID:NP_005736
Protein GI:32171186
UniProt ID:P51572
mRNA ID:NM_005745
Length:246
RefSeq Status:
Protein sequence is identical to GI:213511012 (mRNA isoform)
 
B-cell receptor-associated protein 31 isoform b
Refseq ID:NP_001243376
Protein GI:374253794
UniProt ID:P51572
mRNA ID:NM_001256447
Length:246
RefSeq Status:
Protein sequence is identical to GI:213511012 (mRNA isoform)