MitoProteome Database

MT000788

Gene Information

Entrez Gene ID	10533
Gene Name	autophagy related 7
Gene Symbol	ATG7
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005930	ISS:UniProtKB	C	axoneme
GO:0005737	IDA:UniProtKB	C	cytoplasm
GO:0005829	IBA:RefGenome	C	cytosol
GO:0000407	IBA:RefGenome	C	pre-autophagosomal structure
GO:0019778	ISS:UniProtKB	F	Atg12 activating enzyme activity
GO:0019779	IBA:RefGenome	F	Atg8 activating enzyme
GO:0042803	IDA:UniProtKB	F	protein homodimerization activity
GO:0008134	IPI:UniProtKB	F	transcription factor binding
GO:0004839	TAS:ProtInc	F	ubiquitin activating enzyme activity
GO:0007628	IEA:Ensembl	P	adult walking behavior
GO:0055013	IEA:Ensembl	P	cardiac muscle cell development
GO:0006520	IEA:Ensembl	P	cellular amino acid metabolic process
GO:0006464	TAS:ProtInc	P	cellular protein modification process
GO:0071455	IDA:UniProtKB	P	cellular response to hyperoxia
GO:0006995	IBA:RefGenome	P	cellular response to nitrogen starvation
GO:0009267	IDA:UniProtKB	P	cellular response to starvation
GO:0021955	IEA:Ensembl	P	central nervous system neuron axonogenesis
GO:0021680	IEA:Ensembl	P	cerebellar Purkinje cell layer development
GO:0021987	IEA:Ensembl	P	cerebral cortex development
GO:0006501	IBA:RefGenome	P	C-terminal protein lipidation
GO:0044805	IBA:RefGenome	P	late nucleophagy
GO:0001889	IEA:Ensembl	P	liver development
GO:0061025	TAS:ProtInc	P	membrane fusion
GO:0000422	IBA:RefGenome	P	mitochondrion degradation
GO:0007005	IEA:Ensembl	P	mitochondrion organization
GO:0043066	IEA:Ensembl	P	negative regulation of apoptotic process
GO:0039689	IEA:Ensembl	P	negative stranded viral RNA replication
GO:0050877	IEA:Ensembl	P	neurological system process
GO:0034727	IBA:RefGenome	P	piecemeal microautophagy of nucleus
GO:0043065	IMP:UniProtKB	P	positive regulation of apoptotic process
GO:0010508	IMP:UniProtKB	P	positive regulation of autophagy
GO:0016239	IMP:BHF-UCL	P	positive regulation of macroautophagy
GO:0045732	IMP:UniProtKB	P	positive regulation of protein catabolic process
GO:0031401	IDA:MGI	P	positive regulation of protein modification process
GO:0009791	IEA:Ensembl	P	post-embryonic development
GO:0030163	IBA:RefGenome	P	protein catabolic process
GO:0006497	IDA:MGI	P	protein lipidation
GO:0032446	IBA:RefGenome	P	protein modification by small protein conjugation
GO:0015031	IEA:UniProtKB-KW	P	protein transport
GO:0021860	IEA:Ensembl	P	pyramidal neuron development
GO:0031396	IEA:Ensembl	P	regulation of protein ubiquitination

KEGG Pathway Links

KEGG Pathway ID	Description
hsa04140	Regulation of autophagy
ko04140	Regulation of autophagy

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_75774	Adaptive Immune System
REACT_75842	Antigen processing: Ubiquitination & Proteasome degradation
REACT_75820	Class I MHC mediated antigen processing & presentation
REACT_6900	Immune System