MitoProteome Database

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MT000808

UniProt Annotations

Entry Information

Gene Name	aldehyde dehydrogenase 1 family, member L1
Protein Entry	AL1L1_HUMAN
UniProt ID	O75891
Species	Human

Comments

Comment type	Description
Alternative Products	Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=O75891-1; Sequence=Displayed; Name=2; IsoId=O75891-2; Sequence=VSP_045569; Note=No experimental confirmation available.; Name=3; IsoId=O75891-3; Sequence=VSP_047260;
Catalytic Activity	10-formyltetrahydrofolate + NADP(+) + H(2)O = tetrahydrofolate + CO(2) + NADPH.
Similarity	Contains 1 acyl carrier domain. {ECO:0000255\|PROSITE- ProRule:PRU00258}.
Similarity	In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. {ECO:0000305}.
Similarity	In the N-terminal section; belongs to the GART family. {ECO:0000305}.
Subcellular Location	Cytoplasm.
Tissue Specificity	Highly expressed in liver, pancreas and kidney. {ECO:0000269\|PubMed:20498374}.