MitoProteome Database

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MT000843

UniProt Annotations

Entry Information

Gene Name	ATP-binding cassette, sub-family B (MDR/TAP), member 8
Protein Entry	ABCB8_HUMAN
UniProt ID	Q9NUT2
Species	Human

Comments

Comment type	Description
Alternative Products	Event=Alternative splicing; Named isoforms=5; Name=1; Synonyms=Long; IsoId=Q9NUT2-1; Sequence=Displayed; Name=2; Synonyms=Short; IsoId=Q9NUT2-2; Sequence=VSP_000026; Note=No experimental confirmation available.; Name=3; IsoId=Q9NUT2-3; Sequence=VSP_000026, VSP_055297; Note=No experimental confirmation available.; Name=4; IsoId=Q9NUT2-4; Sequence=VSP_056745; Note=No experimental confirmation available.; Name=5; IsoId=Q9NUT2-5; Sequence=VSP_056744; Note=No experimental confirmation available.;
Similarity	Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily. {ECO:0000305}.
Similarity	Contains 1 ABC transmembrane type-1 domain. {ECO:0000255\|PROSITE-ProRule:PRU00441}.
Similarity	Contains 1 ABC transporter domain. {ECO:0000255\|PROSITE-ProRule:PRU00434}.
Subcellular Location	Mitochondrion inner membrane {ECO:0000269\|PubMed:16259955}; Multi-pass membrane protein {ECO:0000255\|PROSITE-ProRule:PRU00441, ECO:0000269\|PubMed:16259955}.
Subunit	Monomer. {ECO:0000305}.
Tissue Specificity	Ubiquitous.
Web Resource	Name=ABCMdb; Note=Database for mutations in ABC proteins; URL="http://abcmutations.hegelab.org/proteinDetails?uniprot_id=Q9NUT2";