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MT000869

UniProt Annotations

Entry Information

Gene Name	autophagy related 2A
Protein Entry	ATG2A_HUMAN
UniProt ID	Q2TAZ0
Species	Human

Comments

Comment type	Description
Alternative Products	Event=Alternative splicing; Named isoforms=4; Name=1; IsoId=Q2TAZ0-1; Sequence=Displayed; Name=2; IsoId=Q2TAZ0-3; Sequence=VSP_030515; Note=No experimental confirmation available.; Name=3; IsoId=Q2TAZ0-4; Sequence=VSP_030510, VSP_030516; Note=No experimental confirmation available.; Name=4; IsoId=Q2TAZ0-5; Sequence=VSP_030511, VSP_030512; Note=No experimental confirmation available.;
Function	Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion. {ECO:0000269\|PubMed:22219374}.
Interaction	O95166:GABARAP; NbExp=2; IntAct=EBI-2514077, EBI-712001; Q9H0R8:GABARAPL1; NbExp=3; IntAct=EBI-2514077, EBI-746969; P60520:GABARAPL2; NbExp=2; IntAct=EBI-2514077, EBI-720116; Q9GZQ8:MAP1LC3B; NbExp=2; IntAct=EBI-2514077, EBI-373144;
Sequence Caution	Sequence=BAA23700.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
Similarity	Belongs to the ATG2 family. {ECO:0000305}.
Subcellular Location	Preautophagosomal structure membrane; Peripheral membrane protein. Lipid droplet.