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MT000897

Record overview

MITO IDMT000897
Gene ID23576
SpeciesHomo sapiens (Human)
Gene Namedimethylarginine dimethylaminohydrolase 1
Gene SymbolDDAH1
SynonymsDDAH; HEL-S-16;
Alternate namesN(G),N(G)-dimethylarginine dimethylaminohydrolase 1; DDAHI; DDAH-1; dimethylargininase-1; epididymis secretory protein Li 16; NG, NG-dimethylarginine dimethylaminohydrolase;
Chromosome1
Map Location1p22
EC Number3.5.3.18
SummaryThis gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for DDAH1

Proteins

N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 isoform 1
Refseq ID:NP_036269
Protein GI:6912328
UniProt ID:O94760
mRNA ID:NM_012137
Length:285
RefSeq Status:
MAGLGHPAAFGRATHAVVRALPESLGQHALRSAKGEEVDVARAERQHQLYVGVLGSKLGLQVVELPADESLPDCVFVEDVAVVCEETALITRPGAPSRRK
EVDMMKEALEKLQLNIVEMKDENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSMAGPNLIAIGSSESAQKALKI
MQQMSDHRYDKLTVPDDIAANCIYLNIPNKGHVLLHRTPEEYPESAKVYEKLKDHMLIPVSMSELEKVDGLLTCCSVLINKKVDS
 
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 isoform 2
Refseq ID:NP_001127917
Protein GI:197313763
UniProt ID:O94760
mRNA ID:NM_001134445
Length:182
RefSeq Status:
MMKEALEKLQLNIVEMKDENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSMAGPNLIAIGSSESAQKALKIMQQ
MSDHRYDKLTVPDDIAANCIYLNIPNKGHVLLHRTPEEYPESAKVYEKLKDHMLIPVSMSELEKVDGLLTCCSVLINKKVDS