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MT000933

UniProt Annotations

Entry Information

Gene Name	dynamin 3
Protein Entry	DYN3_HUMAN
UniProt ID	Q9UQ16
Species	Human

Comments

Comment type	Description
Alternative Products	Event=Alternative splicing; Named isoforms=5; Name=1; IsoId=Q9UQ16-1; Sequence=Displayed; Name=2; IsoId=Q9UQ16-2; Sequence=VSP_034053; Name=3; IsoId=Q9UQ16-3; Sequence=VSP_034053, VSP_034054; Name=4; IsoId=Q9UQ16-4; Sequence=VSP_034054; Name=5; IsoId=Q9UQ16-5; Sequence=VSP_034053, VSP_054546, VSP_054547; Note=No experimental confirmation available.;
Catalytic Activity	GTP + H(2)O = GDP + phosphate.
Function	Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis (By similarity). {ECO:0000250}.
Sequence Caution	Sequence=BAA74843.2; Type=Erroneous initiation; Evidence={ECO:0000305};
Similarity	Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. {ECO:0000305}.
Similarity	Contains 1 dynamin-type G (guanine nucleotide-binding) domain. {ECO:0000305}.
Similarity	Contains 1 GED domain. {ECO:0000255\|PROSITE- ProRule:PRU00720}.
Similarity	Contains 1 PH domain. {ECO:0000255\|PROSITE- ProRule:PRU00145}.
Subcellular Location	Cytoplasm {ECO:0000305}. Cytoplasm, cytoskeleton {ECO:0000305}. Note=Microtubule-associated. {ECO:0000305}.