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MT001035

UniProt Annotations

Entry Information

Gene Name	coenzyme Q4
Protein Entry	COQ4_HUMAN
UniProt ID	Q9Y3A0
Species	Human

Comments

Comment type	Description
Alternative Products	Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9Y3A0-1; Sequence=Displayed; Name=2; IsoId=Q9Y3A0-2; Sequence=VSP_036866;
Function	Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides. {ECO:0000255\|HAMAP- Rule:MF_03111, ECO:0000269\|PubMed:18474229}.
Pathway	Cofactor biosynthesis; ubiquinone biosynthesis. {ECO:0000255\|HAMAP-Rule:MF_03111}.
Similarity	Belongs to the COQ4 family. {ECO:0000255\|HAMAP- Rule:MF_03111}.
Subcellular Location	Isoform 1: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Subunit	Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. {ECO:0000255\|HAMAP-Rule:MF_03111}.
Tissue Specificity	Expressed ubiquitously, but at high levels in liver, lung and pancreas. {ECO:0000269\|PubMed:18474229}.