MitoProteome Database

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MT001089

Gene Information

Entrez Gene ID	54541
Gene Name	DNA-damage-inducible transcript 4
Gene Symbol	DDIT4
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	IDA:UniProtKB	C	cytoplasm
GO:0005622	IDA:LIFEdb	C	intracellular
GO:0005739	IEA:UniProtKB-KW	C	mitochondrion
GO:0007420	ISS:UniProtKB	P	brain development
GO:0008283	ISS:UniProtKB	P	cell proliferation
GO:0051607	IEA:UniProtKB-KW	P	defense response to virus
GO:0042771	ISS:UniProtKB	P	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0045820	IEA:Ensembl	P	negative regulation of glycolytic process
GO:1902532	ISS:UniProtKB	P	negative regulation of intracellular signal transduction
GO:0033137	ISS:UniProtKB	P	negative regulation of peptidyl-serine phosphorylation
GO:0010801	ISS:UniProtKB	P	negative regulation of peptidyl-threonine phosphorylation
GO:0032007	IMP:UniProtKB	P	negative regulation of TOR signaling
GO:0030182	ISS:UniProtKB	P	neuron differentiation
GO:0001764	ISS:UniProtKB	P	neuron migration
GO:0048011	ISS:UniProtKB	P	neurotrophin TRK receptor signaling pathway
GO:1901216	ISS:UniProtKB	P	positive regulation of neuron death
GO:0043241	IEA:Ensembl	P	protein complex disassembly
GO:0072593	IEA:Ensembl	P	reactive oxygen species metabolic process
GO:0001666	IDA:UniProtKB	P	response to hypoxia

KEGG Pathway Links

KEGG Pathway ID	Description
hsa05206	MicroRNAs in cancer
ko05206	MicroRNAs in cancer
hsa04150	mTOR signaling pathway
ko04150	mTOR signaling pathway
hsa04151	PI3K-Akt signaling pathway
ko04151	PI3K-Akt signaling pathway