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MT001117

UniProt Annotations

Entry Information

Gene Name	aurora kinase A interacting protein 1
Protein Entry	AKIP_HUMAN
UniProt ID	Q9NWT8
Species	Human

Comments

Comment type	Description
Function	May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation.
Interaction	O14965:AURKA; NbExp=2; IntAct=EBI-448665, EBI-448680;
Sequence Caution	Sequence=AAH22808.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Subcellular Location	Mitochondrion {ECO:0000269\|PubMed:23908630}. Nucleus {ECO:0000269\|PubMed:23908630}.
Subunit	Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins. Interacts with Aurora-A. {ECO:0000269\|PubMed:12244051, ECO:0000269\|PubMed:23908630}.
Tissue Specificity	Ubiquitously expressed and especially highly expressed in heart, skeletal muscle and testis.