MitoProteome Database

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MT001133

UniProt Annotations

Entry Information

Gene Name	autophagy related 2B
Protein Entry	ATG2B_HUMAN
UniProt ID	Q96BY7
Species	Human

Comments

Comment type	Description
Function	Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion. {ECO:0000269\|PubMed:22219374}.
Sequence Caution	Sequence=BAA91504.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAB70872.1; Type=Erroneous termination; Positions=800; Note=Translated as Glu.; Evidence={ECO:0000305}; Sequence=BAC87363.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Similarity	Belongs to the ATG2 family. {ECO:0000305}.
Subcellular Location	Preautophagosomal structure membrane {ECO:0000269\|PubMed:22219374}; Peripheral membrane protein {ECO:0000269\|PubMed:22219374}. Lipid droplet {ECO:0000269\|PubMed:22219374}.