MitoProteome Database

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MT001157

UniProt Annotations

Entry Information

Gene Name	abhydrolase domain containing 10
Protein Entry	ABHDA_HUMAN
UniProt ID	Q9NUJ1
Species	Human

Comments

Comment type	Description
Alternative Products	Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q9NUJ1-1; Sequence=Displayed; Name=2; IsoId=Q9NUJ1-2; Sequence=VSP_056093; Note=No experimental confirmation available.; Name=3; IsoId=Q9NUJ1-3; Sequence=VSP_056742, VSP_056743; Note=No experimental confirmation available. Gene prediction based on EST data.;
Catalytic Activity	Mycophenolic acid O-acyl-glucuronide + H(2)O = mycophenolate + D-glucuronate. {ECO:0000269\|PubMed:22294686}.
Function	Catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate. {ECO:0000269\|PubMed:22294686}.
Similarity	Belongs to the AB hydrolase superfamily. {ECO:0000305}.
Subcellular Location	Mitochondrion {ECO:0000305}.