MitoProteome Database

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MT001177

UniProt Annotations

Entry Information

Gene Name	DEAH (Asp-Glu-Ala-His) box polypeptide 32
Protein Entry	DHX32_HUMAN
UniProt ID	Q7L7V1
Species	Human

Comments

Comment type	Description
Alternative Products	Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q7L7V1-1; Sequence=Displayed; Name=2; IsoId=Q7L7V1-2; Sequence=VSP_026427;
Catalytic Activity	ATP + H(2)O = ADP + phosphate.
Induction	Up-regulated by ionomycin in T-lymphocytes. Down- regulated in acute lymphoblastic leukemia. {ECO:0000269\|PubMed:12163057, ECO:0000269\|PubMed:16414036}.
Sequence Caution	Sequence=AAH37925.1; Type=Frameshift; Positions=439; Evidence={ECO:0000305}; Sequence=BAB15029.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Similarity	Belongs to the DEAD box helicase family. DEAH subfamily. {ECO:0000305}.
Similarity	Contains 1 helicase ATP-binding domain. {ECO:0000255\|PROSITE-ProRule:PRU00541}.
Similarity	Contains 1 helicase C-terminal domain. {ECO:0000305}.
Subcellular Location	Nucleus {ECO:0000269\|PubMed:16959245}. Mitochondrion {ECO:0000269\|PubMed:16959245}.
Tissue Specificity	Expressed in lymphoid tissues (at protein level). Expressed in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung, lymphoid tissues and blood leukocytes. {ECO:0000269\|PubMed:12163057, ECO:0000269\|PubMed:16181624}.