MitoProteome Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MT001259

Record overview

MITO IDMT001259
Gene ID64422
SpeciesHomo sapiens (Human)
Gene Nameautophagy related 3
Gene SymbolATG3
SynonymsAPG3; APG3L; PC3-96; APG3-LIKE;
Alternate namesubiquitin-like-conjugating enzyme ATG3; hApg3; 2610016C12Rik; autophagy-related protein 3; ATG3 autophagy related 3 homolog;
Chromosome3
Map Location3q13.2
EC Number6.3.2.-
SummaryThis gene encodes a ubiquitin-like-conjugating enzyme and is a component of ubiquitination-like systems involved in autophagy, the process of degradation, turnover and recycling of cytoplasmic constituents in eukaryotic cells. This protein is known to play a role in regulation of autophagy during cell death. A pseudogene of this gene is located on chromosome 20. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
OrthologsView orthologs and multiple alignments for ATG3

Proteins

ubiquitin-like-conjugating enzyme ATG3 isoform 1
Refseq ID:NP_071933
Protein GI:19526773
UniProt ID:Q9NT62
mRNA ID:NM_022488
Length:314
RefSeq Status:
MQNVINTVKGKALEVAEYLTPVLKESKFKETGVITPEEFVAAGDHLVHHCPTWQWATGEELKVKAYLPTGKQFLVTKNVPCYKRCKQMEYSDELEAIIEE
DDGDGGWVDTYHNTGITGITEAVKEITLENKDNIRLQDCSALCEEEEDEDEGEAADMEEYEESGLLETDEATLDTRKIVEACKAKTDAGGEDAILQTRTY
DLYITYDKYYQTPRLWLFGYDEQRQPLTVEHMYEDISQDHVKKTVTIENHPHLPPPPMCSVHPCRHAEVMKKIIETVAEGGGELGVHMYLLIFLKFVQAV
IPTIEYDYTRHFTM
 
ubiquitin-like-conjugating enzyme ATG3 isoform 2
Refseq ID:NP_001265641
Protein GI:523704487
UniProt ID:Q9NT62
mRNA ID:NM_001278712
Length:311
RefSeq Status:
MQNVINTVKGKALEVAEYLTPVLKESKFKETGVITPEEFVAAGDHLVHHCPTWQWATGEELKVKAYLPTGKQFLVTKNVPCYKRCKQMEYSDELEAIIEE
DDGDGGWVDTYHNTGITGITEAVKEITLENKDNIRLQDCSALCEEEEDEDEGEAADMEEYEESGLLETDEATLDTRKIVEACKAKTDAGGEDAILQTRTY
DLYITYDKYYQTPRLWLFGYDEQRQPLTVEHMYEDISQDHVKKTVTIENHPHLPPPPMCSVHPCRHAEVMKKIIETVAEGGGELGVHMYPSLYVRLVAKW
LLTIFFLRNLV