MitoProteome Database

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MT001357

Gene Information

Entrez Gene ID80347
Gene NameCoA synthase
Gene SymbolCOASY
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0070062 IDA:UniProtCextracellular vesicular exosome
GO:0005759 IDA:UniProtKBCmitochondrial matrix
GO:0005741 TAS:ReactomeCmitochondrial outer membrane
GO:0005634 IDA:HPACnucleus
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0004140 IDA:UniProtKBFdephospho-CoA kinase activity
GO:0004595 IDA:UniProtKBFpantetheine-phosphate adenylyltransferase activity
GO:0008219 IEA:UniProtKB-KWPcell death
GO:0015937 IDA:UniProtKBPcoenzyme A biosynthetic process
GO:0009108 TAS:ReactomePcoenzyme biosynthetic process
GO:0015939 TAS:ReactomePpantothenate metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006766 TAS:ReactomePvitamin metabolic process
GO:0006767 TAS:ReactomePwater-soluble vitamin metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa_M00120Coenzyme A biosynthesis, pantothenate => CoA
M00120Coenzyme A biosynthesis, pantothenate => CoA
hsa01100Metabolic pathways
hsa00770Pantothenate and CoA biosynthesis
ko00770Pantothenate and CoA biosynthesis
BIOCYC Pathway Links
BIOCYC Pathway IDDescription
COA-PWYcoenzyme A biosynthesis
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_11218Coenzyme A biosynthesis
REACT_169280Defective AMN causes hereditary megaloblastic anemia 1
REACT_169403Defective BTD causes biotidinase deficiency
REACT_169178Defective CD320 causes methylmalonic aciduria
REACT_169132Defective CUBN causes hereditary megaloblastic anemia 1
REACT_169415Defective GIF causes intrinsic factor deficiency
REACT_169312Defective HLCS causes multiple carboxylase deficiency
REACT_169363Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
REACT_169316Defective MMAA causes methylmalonic aciduria type cblA
REACT_169318Defective MMAB causes methylmalonic aciduria type cblB
REACT_169169Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
REACT_169256Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
REACT_169149Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
REACT_169439Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
REACT_169313Defective MUT causes methylmalonic aciduria mut type
REACT_169120Defective TCN2 causes hereditary megaloblastic anemia
REACT_169238Defects in biotin (Btn) metabolism
REACT_169429Defects in cobalamin (B12) metabolism
REACT_169385Defects in vitamin and cofactor metabolism
REACT_116125Disease
REACT_111217Metabolism
REACT_11193Metabolism of vitamins and cofactors
REACT_11238Metabolism of water-soluble vitamins and cofactors
REACT_11172Vitamin B5 (pantothenate) metabolism