MitoProteome Database

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MT001358

UniProt Annotations

Entry Information

Gene Name	acyl-CoA dehydrogenase family, member 10
Protein Entry	ACD10_HUMAN
UniProt ID	Q6JQN1
Species	Human

Comments

Comment type	Description
Alternative Products	Event=Alternative splicing; Named isoforms=5; Name=1; IsoId=Q6JQN1-1; Sequence=Displayed; Name=2; IsoId=Q6JQN1-2; Sequence=VSP_024634, VSP_024635; Name=3; IsoId=Q6JQN1-3; Sequence=VSP_024630, VSP_024633, VSP_024634, VSP_024635; Note=No experimental confirmation available.; Name=4; IsoId=Q6JQN1-4; Sequence=VSP_024631, VSP_024632; Note=No experimental confirmation available.; Name=5; IsoId=Q6JQN1-5; Sequence=VSP_044980; Note=No experimental confirmation available.;
Catalytic Activity	Acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor.
Cofactor	Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000250};
Function	Acyl-CoA dehydrogenase only active with R- and S-2- methyl-C15-CoA. {ECO:0000269\|PubMed:21237683}.
Sequence Caution	Sequence=AAH15056.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Similarity	Belongs to the acyl-CoA dehydrogenase family. {ECO:0000305}.
Tissue Specificity	Widely expressed with highest expression in fetal brain, followed by heart, muscle, kidney and adult brain. Expression levels varying from isoform to isoform. {ECO:0000269\|PubMed:15560374, ECO:0000269\|PubMed:21237683}.