MitoProteome Database

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MT001401

UniProt Annotations

Entry Information

Gene Name	coenzyme Q5 homolog, methyltransferase (S. cerevisiae)
Protein Entry	COQ5_HUMAN
UniProt ID	Q5HYK3
Species	Human

Comments

Comment type	Description
Alternative Products	Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q5HYK3-1; Sequence=Displayed; Name=2; IsoId=Q5HYK3-2; Sequence=VSP_017681, VSP_017682; Note=No experimental confirmation available.;
Catalytic Activity	S-adenosyl-L-methionine + 2-methoxy-6-all- trans-polyprenyl-1,4-benzoquinol = S-adenosyl-L-homocysteine + 6- methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol.
Function	Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). {ECO:0000250}.
Pathway	Cofactor biosynthesis; ubiquinone biosynthesis.
Similarity	Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiE family. {ECO:0000305}.
Subcellular Location	Mitochondrion {ECO:0000250}.