MitoProteome Database

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MT001430

Record overview

MITO IDMT001430
Gene ID84883
SpeciesHomo sapiens (Human)
Gene Nameapoptosis-inducing factor, mitochondrion-associated, 2
Gene SymbolAIFM2
SynonymsAMID; PRG3;
Alternate namesapoptosis-inducing factor 2; p53-responsive gene 3 protein; apoptosis-inducing factor (AIF)-like mitochondrion-associated inducer of death; apoptosis-inducing factor (AIF)-homologous mitochondrion-associated inducer of death;
Chromosome10
Map Location10q22.1
EC Number1.-.-.-
SummaryThis gene encodes a flavoprotein oxidoreductase that binds single stranded DNA and is thought to contribute to apoptosis in the presence of bacterial and viral DNA. The expression of this gene is also found to be induced by tumor suppressor protein p53 in colon cancer cells. [provided by RefSeq, Nov 2010]
OrthologsView orthologs and multiple alignments for AIFM2

Proteins

apoptosis-inducing factor 2
Refseq ID:NP_116186
Protein GI:14318424
UniProt ID:Q9BRQ8
mRNA ID:NM_032797
Length:373
RefSeq Status:
MGSQVSVESGALHVVIVGGGFGGIAAASQLQALNVPFMLVDMKDSFHHNVAALRASVETGFAKKTFISYSVTFKDNFRQGLVVGIDLKNQMVLLQGGEAL
PFSHLILATGSTGPFPGKFNEVSSQQAAIQAYEDMVRQVQRSRFIVVVGGGSAGVEMAAEIKTEYPEKEVTLIHSQVALADKELLPSVRQEVKEILLRKG
VQLLLSERVSNLEELPLNEYREYIKVQTDKGTEVATNLVILCTGIKINSSAYRKAFESRLASSGALRVNEHLQVEGHSNVYAIGDCADVRTPKMAYLAGL
HANIAVANIVNSVKQRPLQAYKPGALTFLLSMGRNDGVGQISGFYVGRLMVRLTKSRDLFVSTSWKTMRQSPP
 
apoptosis-inducing factor 2
Refseq ID:NP_001185625
Protein GI:311082415
UniProt ID:Q9BRQ8
mRNA ID:NM_001198696
Length:373
RefSeq Status:
Protein sequence is identical to GI:14318424 (mRNA isoform)