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MT001514

Record overview

MITO IDMT001514
Gene ID124454
SpeciesHomo sapiens (Human)
Gene Nameglutamyl-tRNA synthetase 2, mitochondrial
Gene SymbolEARS2
SynonymsMSE1; COXPD12;
Alternate namesprobable glutamate--tRNA ligase, mitochondrial; gluRS; glutamate--tRNA ligase; glutamate tRNA ligase 2, mitochondrial; probable glutamyl-tRNA synthetase, mitochondrial; glutamyl-tRNA synthetase 2, mitochondrial (putative);
Chromosome16
Map Location16p12.2
EC Number6.1.1.17
SummaryAminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene belongs to the class-I aminoacyl-tRNA synthetase family and catalyzes the attachment of glutamate to tRNA(Glu). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010]
OrthologsView orthologs and multiple alignments for EARS2

Proteins

probable glutamate--tRNA ligase, mitochondrial
Refseq ID:NP_001077083
Protein GI:134288884
UniProt ID:Q5JPH6
mRNA ID:NM_001083614
Length:523
RefSeq Status:
MAALLRRLLQRERPSAASGRPVGRREANLGTDAGVAVRVRFAPSPTGFLHLGGLRTALYNYIFAKKYQGSFILRLEDTDQTRVVPGAAENIEDMLEWAGI
PPDESPRRGGPAGPYQQSQRLELYAQATEALLKTGAAYPCFCSPQRLELLKKEALRNHQTPRYDNRCRNMSQEQVAQKLAKDPKPAIRFRLEQVVPAFQD
LVYGWNRHEVASVEGDPVIMKSDGFPTYHLACVVDDHHMGISHVLRGSEWLVSTAKHLLLYQALGWQPPHFAHLPLLLNRDGSKLSKRQGDVFLEHFAAD
GFLPDSLLDIITNCGSGFAENQMGRTLPELITQFNLTQVTCHSALLDLEKLPEFNRLHLQRLVSNESQRRQLVGKLQVLVEEAFGCQLQNRDVLNPVYVE
RILLLRQGHICRLQDLVSPVYSYLWTRPAVGRAQLDAISEKVDVIAKRVLGLLERSSMSLTQDMLNGELKKLSEGLEGTKYSNVMKLLRMALSGQQQGPP
VAEMMLALGPKEVRERIQKVVSS