MitoProteome Database

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MT001551

UniProt Annotations

Entry Information

Gene Name	BRI3 binding protein
Protein Entry	BRI3B_HUMAN
UniProt ID	Q8WY22
Species	Human

Comments

Comment type	Description
Function	Involved in tumorigenesis and may function by stabilizing p53/TP53. {ECO:0000269\|PubMed:17943721}.
Sequence Caution	Sequence=AAL33003.2; Type=Frameshift; Positions=43, 47, 59; Evidence={ECO:0000305};
Subcellular Location	Mitochondrion outer membrane {ECO:0000305\|PubMed:17943721}; Multi-pass membrane protein {ECO:0000305\|PubMed:17943721}.
Subunit	Interacts with LETMD1. {ECO:0000269\|PubMed:17943721}.
Tissue Specificity	Most abundantly expressed in brain, liver and kidney. Overexpressed in leukemia and lymphoma cell lines, as well as in various carcinomas. {ECO:0000269\|PubMed:11860200, ECO:0000269\|PubMed:17943721}.